NCT05327452Active, not recruiting
Testing Home-based Exercise Strategies in Underserved Minority Cancer Patients Undergoing Chemotherapy: the THRIVE Study
Testing Home-based Exercise Strategies to Improve Exercise Participation and Cardiovascular Health in Underserved Minority Patients With Cancer Undergoing Chemotherapy: the THRIVE Study
Source: ClinicalTrials.gov · Last updated 21 Jan 2026
Brief summary (registry, in English)
The purpose of this research is to determine whether a 16 week, home-based, aerobic and resistance exercise intervention will increase physical activity levels in Black and Hispanic breast, colorectal, or prostate cancer patients. The names of the study interventions involved in this study are: * Supervised aerobic and resistance exercise (SUP) - virtually supervised 16- week aerobic and resistance exercise performed at home via Zoom. * Unsupervised aerobic and resistance exercise (UNSUP) - home-based 16- week aerobic and resistance exercise. * Attention control (AC) - 16-week home-based stretching.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 135 (estimated)
- First submitted
- 11 Mar 2022
- Start date
- 31 Oct 2022
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Dana-Farber Cancer Institute
- Diseases
- Prostate cancer, Colorectal cancer
- NCT number
- NCT05327452
What you commit to
- Study type: Interventional
- Planned participants: 135
- From 31 Oct 2022 to the primary completion date, 31 Dec 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Pre-existing musculoskeletal or cardiorespiratory conditions
- Patients should not have any uncontrolled illness including ongoing or active infection, uncontrolled diabetes, hypertension, or thyroid disease
- Patients with other active malignancies
- Patients with metastatic disease
- Unable to travel to Dana-Farber Cancer Institute for necessary data collection
Other
- Participate in more than 90 minutes of structured exercise/week
- Subjects, who in the opinion of the investigator, may not be able to comply with the safety monitoring requirements of the study.
Who the study is looking for
- Over 18 years old; children under the age of 18 will be excluded due to rarity of disease
- Newly diagnosed with stage I-III breast, colorectal or prostate cancer
- Self-identify as Hispanic or Black
- Are within 4 weeks of initiating chemotherapy
- Overweight or obese (BMI \>25kg/m2 or body fat percent \>30)
- Physician's clearance to participate in moderate-vigorous intensity exercise
- Speak English or Spanish
- Engaging in less than 90 minutes of moderate-or-vigorous physical activity per week
- Willing to travel to Dana-Farber Cancer Institute for necessary data collection
- Ability to understand and the willingness to sign a written informed consent document.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dana-Farber Cancer Institute Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.