NCT05328765Completed
A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection
ACTION HIV (Anal Cancer TherapIes and Outcomes iNitiative for Patients Living With and Without HIV): A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 369 (actual)
- First submitted
- 5 Apr 2022
- Start date
- 9 Jun 2023
- Primary completion date
- 7 Feb 2025
- Lead sponsor
- Latin American Cooperative Oncology Group
- Diseases
- HIV
- NCT number
- NCT05328765
What you commit to
- Study type: Observational
- Participants enrolled: 369
- From 9 Jun 2023 to the primary completion date, 7 Feb 2025
- 11 sites in 5 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Lack of data on treatments and clinical outcomes
Who the study is looking for
- Patients 18 years of age or older
- Confirmed histological diagnosis of anal canal squamous cell carcinoma. Basaloid subtype is accepted
- Have underundered serological test for HIV infection
- Any clinical stage
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (11)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital de Gastroenterología Carlos Bonorino Udaondo Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Unknown status |
| Hospital de Amor de Barretos Coordinator of this site? Confirm its status | Barretos | Brazil | Unknown status |
| CEPON - Centro de Pesquisas Oncologicas Coordinator of this site? Confirm its status | Florianópolis | Brazil | Unknown status |
| HUOL - Hospital Universitário Onofre Lopes da UFRN Coordinator of this site? Confirm its status | Natal | Brazil | Unknown status |
| Liga Norte Riograndense Contra o Cancer Coordinator of this site? Confirm its status | Natal | Brazil | Unknown status |
| INCA - Instituto Nacional de Câncer Coordinator of this site? Confirm its status | Rio de Janeiro | Brazil | Unknown status |
| A.C. Camargo Cancer Center Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| INCan - Instituto Nacional de Cancerología Coordinator of this site? Confirm its status | Mexico City | Mexico | Unknown status |
| Oncosalud AUNA Coordinator of this site? Confirm its status | Lima | Peru | Unknown status |
| INEN - Instituto Nacional de Enfermedades Neoplásicas Coordinator of this site? Confirm its status | Lima | Peru | Unknown status |
| Hospital de Clínicas de Montevideo Dr. Manuel Quintela Coordinator of this site? Confirm its status | Montevideo | Uruguay | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.