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NCT05328765Completed

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

ACTION HIV (Anal Cancer TherapIes and Outcomes iNitiative for Patients Living With and Without HIV): A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Source: ClinicalTrials.gov · Last updated 28 Aug 2026

Brief summary (registry, in English)

Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.

Status (registry)
Completed
Study type
Observational
Enrollment
369 (actual)
First submitted
5 Apr 2022
Start date
9 Jun 2023
Primary completion date
7 Feb 2025
Lead sponsor
Latin American Cooperative Oncology Group
Diseases
HIV
NCT number
NCT05328765

What you commit to

  • Study type: Observational
  • Participants enrolled: 369
  • From 9 Jun 2023 to the primary completion date, 7 Feb 2025
  • 11 sites in 5 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Lack of data on treatments and clinical outcomes

Who the study is looking for

  • Patients 18 years of age or older
  • Confirmed histological diagnosis of anal canal squamous cell carcinoma. Basaloid subtype is accepted
  • Have underundered serological test for HIV infection
  • Any clinical stage

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (11)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hospital de Gastroenterología Carlos Bonorino Udaondo
Coordinator of this site? Confirm its status
Buenos AiresArgentinaUnknown status
Hospital de Amor de Barretos
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BarretosBrazilUnknown status
CEPON - Centro de Pesquisas Oncologicas
Coordinator of this site? Confirm its status
FlorianópolisBrazilUnknown status
HUOL - Hospital Universitário Onofre Lopes da UFRN
Coordinator of this site? Confirm its status
NatalBrazilUnknown status
Liga Norte Riograndense Contra o Cancer
Coordinator of this site? Confirm its status
NatalBrazilUnknown status
INCA - Instituto Nacional de Câncer
Coordinator of this site? Confirm its status
Rio de JaneiroBrazilUnknown status
A.C. Camargo Cancer Center
Coordinator of this site? Confirm its status
São PauloBrazilUnknown status
INCan - Instituto Nacional de Cancerología
Coordinator of this site? Confirm its status
Mexico CityMexicoUnknown status
Oncosalud AUNA
Coordinator of this site? Confirm its status
LimaPeruUnknown status
INEN - Instituto Nacional de Enfermedades Neoplásicas
Coordinator of this site? Confirm its status
LimaPeruUnknown status
Hospital de Clínicas de Montevideo Dr. Manuel Quintela
Coordinator of this site? Confirm its status
MontevideoUruguayUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.