NCT05334927Recruiting
China HeadAche DIsorders RegiStry
Source: ClinicalTrials.gov · Last updated 10 Jul 2026
Brief summary (registry, in English)
It is planned to include 10000 patients. In the China HeadAche DIsorders RegiStry CHAIRS), patients aged over 12 years with primary headache and medication-overuse headache(MOH) were collected. The biomarkers, imaging features, cognition, genetic characteristics, ocial and demographic data, medical data, therapeutics used, and outcome of headache-related diseases were studied, and long-term follow-up was planned.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 10000 (estimated)
- First submitted
- 20 Jan 2022
- Start date
- 29 Aug 2022
- Primary completion date
- 31 Dec 2031
- Lead sponsor
- Beijing Tiantan Hospital
- Diseases
- Migraine
- NCT number
- NCT05334927
What you commit to
- Study type: Observational
- Planned participants: 10000
- From 29 Aug 2022 to the primary completion date, 31 Dec 2031
- 61 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- According to the ICHD-3 diagnostic criteria, there are still headaches directly related to secondary factors (except drug overuse) at the time of enrollment;
- Those who cannot be diagnosed as primary headache or primary headache combined with medication overuse headache according to ICHD-3;
Other illness
- According to DSM-V diagnostic criteria, patients with severe mental diseases (such as schizophrenia, mental disorders associated with mental retardation, etc.);
- Patients with severe organic diseases, such as malignant tumors, and the expected survival time is less than 1 year;
Other
- Pregnant,planning pregnancy or Lactating women;
- Subjects participating in other clinical trials;
- Unable to cooperate to complete the follow-up due to geographical or other reasons
Who the study is looking for
- Age ≥ 12 years old,Any gender;
- The first onset age of primary headache was less than 50 years old(Age \<65 years at first diagnosis of chronic migraine);
- patients with primary headache (migraine, tension headache and other types of primary headache) or primary headache complicated with MOH according to ICHD-3;
- Sign the informed consent form.
Age in the registry: 12 years to - · Sex: All · Does not accept healthy volunteers
Sites (61)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Anqing Municipal Hospital Coordinator of this site? Confirm its status | Anqing | China | Recruiting |
| Ansteel Group General Hospital Coordinator of this site? Confirm its status | Anshan | China | Recruiting |
| Baotou Central Hospital Coordinator of this site? Confirm its status | Baotou | China | Recruiting |
| Beijing ChaoYang Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
| Peking University Third Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
| Beijing Tiantan Hospital,Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
| The First Hospital of Fangshan District, Beijing Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
| The Second Hospital of Jilin University Coordinator of this site? Confirm its status | Changchun | China | Recruiting |
| The First Hospital of Jilin University Coordinator of this site? Confirm its status | Changchun | China | Recruiting |
| Changzhou First People's Hospital Coordinator of this site? Confirm its status | Changzhou | China | Recruiting |
| Chengdu Second People's Hospital Coordinator of this site? Confirm its status | Chengdu | China | Recruiting |
| Hospital of Chengdu University of Traditional Chinese Medicine Coordinator of this site? Confirm its status | Chengdu | China | Recruiting |
| Chongqing People's Hospital Coordinator of this site? Confirm its status | Chongqing | China | Recruiting |
| The Third Affiliated Hospital of Chongqing Medical University Coordinator of this site? Confirm its status | Chongqing | China | Recruiting |
| Dachuan District People's Hospital Coordinator of this site? Confirm its status | Dazhou | China | Recruiting |
| Deyang People's Hospital Coordinator of this site? Confirm its status | Deyang | China | Recruiting |
| Fujian Provincial Hospital Coordinator of this site? Confirm its status | Fuzhou | China | Recruiting |
| The First People's Hospital of Guangyuan Coordinator of this site? Confirm its status | Guangyuan | China | Recruiting |
| Guangyuan Hospital of Traditional Chinese Medicin Coordinator of this site? Confirm its status | Guangyuan | China | Recruiting |
| The Second People's Hospital of Guiyang Coordinator of this site? Confirm its status | Guiyang | China | Recruiting |
| The Second Affiliated Hospital of Zhejiang University School of Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Recruiting |
| The Second Affiliated Hospital of Harbin Medical University Coordinator of this site? Confirm its status | Harbin | China | Recruiting |
| Huludao Central Hospital Coordinator of this site? Confirm its status | Huludao | China | Recruiting |
| Huzhou Central Hospital Coordinator of this site? Confirm its status | Huzhou | China | Recruiting |
| Shandong Provincial Hospital Coordinator of this site? Confirm its status | Jinan | China | Recruiting |
| Shandong Provincial Qianfoshan Hospital Coordinator of this site? Confirm its status | Jinan | China | Recruiting |
| Jiujiang First People's Hospital Coordinator of this site? Confirm its status | Jiujiang | China | Recruiting |
| The Second Hospital of Lanzhou University Coordinator of this site? Confirm its status | Lanzhou | China | Recruiting |
| Luohe Central Hospital Coordinator of this site? Confirm its status | Luohe | China | Recruiting |
| Luoyang Central Hospital Coordinator of this site? Confirm its status | Luoyang | China | Recruiting |
| Yiyang County People's Hospital Coordinator of this site? Confirm its status | Luoyang | China | Recruiting |
| The Second Affiliated Hospital of Henan University of Science and Technology Coordinator of this site? Confirm its status | Luoyang | China | Recruiting |
| The First Affiliated Hospital of NanChang University Coordinator of this site? Confirm its status | Nanchang | China | Recruiting |
| Nanchong Central Hospital Coordinator of this site? Confirm its status | Nanchong | China | Recruiting |
| Brain Hospital Affiliated to Nanjing Medical University Coordinator of this site? Confirm its status | Nanjing | China | Recruiting |
| The First Affiliated Hospital of Guangxi University of Chinese Medicine Coordinator of this site? Confirm its status | Nanning | China | Recruiting |
| The Second Affiliated Hospital of Guangxi Medical University Coordinator of this site? Confirm its status | Nanning | China | Recruiting |
| Panzhihua Central Hospital Coordinator of this site? Confirm its status | Panzhihua | China | Recruiting |
| Qinhuangdao Haigang Hospital Coordinator of this site? Confirm its status | Qinhuangdao | China | Recruiting |
| Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine Coordinator of this site? Confirm its status | Qionghai | China | Recruiting |
| Shanghai Jiao Tong University School of Medicine Affiliated Tongren Hospital Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
| Shenzhen Second People's Hospital Coordinator of this site? Confirm its status | Shenzhen | China | Recruiting |
| Siyang Hospital Coordinator of this site? Confirm its status | Siyang | China | Recruiting |
| The Second Hospital of Shanxi Medical University Coordinator of this site? Confirm its status | Taiyuan | China | Recruiting |
| Xinjiang Production and Construction Corps Hospital Coordinator of this site? Confirm its status | Ürümqi | China | Recruiting |
| The First Affiliated Hospital of Wenzhou Medical University Coordinator of this site? Confirm its status | Wenzhou | China | Recruiting |
| Zhongnan Hospital of Wuhan University Coordinator of this site? Confirm its status | Wuhan | China | Recruiting |
| The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital) Coordinator of this site? Confirm its status | Wuhu | China | Recruiting |
| The Second Affiliated Hospital of Xiamen Medical College Coordinator of this site? Confirm its status | Xiamen | China | Recruiting |
| The First Affiliated hospital of Xiamen University Coordinator of this site? Confirm its status | Xiamen | China | Recruiting |
| Qinghe County People's Hospital Coordinator of this site? Confirm its status | Xingtai | China | Recruiting |
| Xuchang Central Hospital Coordinator of this site? Confirm its status | Xuchang | China | Recruiting |
| Zhangjiakou First Hospital Coordinator of this site? Confirm its status | Zhangjiakou | China | Recruiting |
| The First Affiliated Hospital of Hebei North University Coordinator of this site? Confirm its status | Zhangjiakou | China | Recruiting |
| Yangyuan County People's Hospital Coordinator of this site? Confirm its status | Zhangjiakou | China | Recruiting |
| Zhengzhou Central Hospital Coordinator of this site? Confirm its status | Zhengzhou | China | Recruiting |
| The 7th People's Hospital of Zhengzhou Coordinator of this site? Confirm its status | Zhengzhou | China | Recruiting |
| The First Affiliated Hospital of Zhengzhou University Coordinator of this site? Confirm its status | Zhengzhou | China | Recruiting |
| Zibo Municipal Hospital Coordinator of this site? Confirm its status | Zibo | China | Recruiting |
| Zigong First People's Hospital Coordinator of this site? Confirm its status | Zigong | China | Recruiting |
| The first people's hospital of Zunyi Coordinator of this site? Confirm its status | Zunyi | China | Recruiting |
Related publications
- Iron deposition network mapping of disease occurrence and clinical manifestations in migraine: A prospective study.Cephalalgia · 2026 · PMID 41603449
- Abnormal neurovascular coupling in the precuneus associated with migraine chronification: A multimodal magnetic resonance imaging study.Cephalalgia · 2025 · PMID 41223010
This page is information, not medical advice. Discuss any trial with your doctor.