NCT05335122CompletedPhase 2
A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)
A Prospective, Multi-center, Randomized, Parallel-group, Controlled Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant in Subjects With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
To assess efficacy, and safety of a single sustained release dose of the OTX-TIC drug product (2 travoprost dose strengths) in subjects with Open Angle Glaucoma (OAG) or Ocular Hypertension (OHT)
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 83 (actual)
- First submitted
- 12 Apr 2022
- Start date
- 16 Mar 2022
- Primary completion date
- 24 Jan 2024
- Lead sponsor
- Ocular Therapeutix, Inc.
- Diseases
- Glaucoma, High blood pressure
- NCT number
- NCT05335122
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 83
- From 16 Mar 2022 to the primary completion date, 24 Jan 2024
- 29 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have an uncontrolled systemic disease or a debilitating disease (e.g., cardiovascular, hypertension, uncontrolled diabetes)
Other
- Are currently pregnant or breast-feeding or of childbearing potential without the use of adequate contraceptive methods during the length of the study
- Non-responsive to topical prostaglandins, prostamides or prostaglandin analogs
Who the study is looking for
- Are 18 years of age or older at the time of screening
- Provide written informed consent and are able to comply with all study requirements
- Are willing to withhold glaucoma medications according to the study requirements, and in the opinion of the investigator can do so without significant risk
- Have a negative pregnancy test result for women of childbearing potential at Baseline
- Have a documented diagnosis of OHT, or OAG in the study eye
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (29)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Austin | United States | Unknown status |
| Ocular Therapeutix Inc Coordinator of this site? Confirm its status | Carmel | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Clearwater | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Cranberry Township | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Ocular Therapeutiux, Inc. Coordinator of this site? Confirm its status | Delray Beach | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Dothan | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Dover | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | El Paso | United States | Unknown status |
| Ocular Therapeutiux, Inc. Coordinator of this site? Confirm its status | Fargo | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Fort Myers | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Huntington Beach | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Irvine | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Kenosha | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| Ocular Therapeutix Inc Coordinator of this site? Confirm its status | Oklahoma City | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Pasadena | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Petaluma | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Redlands | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Rock Island | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Roswell | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Saint Joseph | United States | Unknown status |
| Ocular Therapeutix Inc. Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Torrance | United States | Unknown status |
| Ocular Therapeutix, Inc. Coordinator of this site? Confirm its status | Troy | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.