NCT05335187Recruiting
Hybrid Micro-macro Electrodes in Patients With Epilepsy
Hybrid Micro-macro Electrodes to Record the Activity of Single Neurons During Seizures in Patients Who Suffer From Epilepsy
Source: ClinicalTrials.gov · Last updated 5 May 2026
Brief summary (registry, in English)
The aim of the MicroEPI study is to know whether it is possible to use safely a medical device (a micro-electrode) that allows recording the activity of neurons in the human brain. Patients who suffer from drug-resistant epilepsy and who are candidates to epilepsy surgery to alleviate their condition sometimes require the implantation of intracranial EEG electrodes for a few weeks, in order to determine as best as possible which region of the brain to operate on. In the MicroEPI study, some of these electrodes will also comprise micro-electrodes, allowing us to record the activity of the patients' neurons during their epileptic seizures.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 1 Apr 2022
- Start date
- 30 Mar 2023
- Primary completion date
- Sept 2027
- Lead sponsor
- Pierre Mégevand
- Diseases
- Epilepsy
- NCT number
- NCT05335187
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 30 Mar 2023 to the primary completion date, Sept 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe concomitant medical disease (including, but not limited to, cardiovascular, respiratory, renal or hepatic disease).
- Severe concomitant psychiatric disease or major psychological distress.
Other illness
- Any acute infection (e.g. fever, throat infection).
- Skin or scalp infection over the implantation site.
- Increased risk of infections, either from a medical condition or from immunosuppressant medication.
- Increased risk of bleeding, either from a medical condition or from antiplatelet or anticoagulant medication.
Other
- Thin or fragile skull bones, which would prevent stereo-EEG electrodes from being anchored safely.
- Women who are pregnant or breastfeeding during the study.
- Patients who have an implanted stimulation device (e.g. pacemaker, defibrillator, neurostimulator).
Who the study is looking for
- Patient 18 years old or older suffering from drug-resistant focal epilepsy.
- Candidate for epilepsy surgery.
- Requires evaluation with intracranial stereo-EEG electrodes.
- Able and willing to provide informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Inselspital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
| Hôpitaux universitaires de Genève Coordinator of this site? Confirm its status | Geneva | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.