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NCT05335603Recruiting

An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis

Fatty Liver Library (FALL): a Prospective Cohort Study Evaluating the Characteristics of Chronic Liver Diseases Associated With Hepatic Steatosis

Source: ClinicalTrials.gov · Last updated 19 Apr 2022 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Hepatic steatosis may cause inflammation and fibrosis within the liver potentially leading to end-stage liver disease cirrhosis, liver failure and death. The condition is associated with several other chronic liver diseases like autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, hereditary hemochromatosis and alpha-1-antitrypsin deficiency and may also develop secondary to other diseases like inflammatory bowel disease and chronic pancreatitis. Diagnosing chronic liver diseases can be challenging and treatment may be limited. In-depth phenotyping at a tissue level may generate insight into the underlying pathophysiology of diseases and furthermore identify common as well as specific diagnostic biomarkers and future treatment targets of the diseases. We therefore undertake a study that evaluates patients with chronic liver diseases associated with hepatic steatosis.

Status (registry)
Recruiting
Study type
Observational
Enrollment
335 (estimated)
First submitted
12 Apr 2022
Start date
24 Aug 2020
Primary completion date
Aug 2036
Lead sponsor
University of Copenhagen
NCT number
NCT05335603

What you commit to

  • Study type: Observational
  • Planned participants: 335
  • From 24 Aug 2020 to the primary completion date, Aug 2036
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • malignant diseases
  • viral hepatitis

Other

  • Patients with:
  • human immunodeficiency virus
  • contraindications to liver biopsy

Who the study is looking for

  • Adult patients/healthy control participants (age 18 or above) who can give their informed consent
  • Suspected liver disease:
  • non-alcoholic steatohepatitis
  • alcoholic steatohepatitis
  • autoimmune hepatitis
  • primary biliary cholangitis
  • primary sclerosing cholangitis
  • inflammatory bowel disease
  • polycystic ovary syndrome
  • hereditary haemochromatosis
  • chronic pancreatitis
  • cystic fibrosis
  • alpha-1 antitrypsin deficiency

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hvidovre University Hospital
Coordinator of this site? Confirm its status
HvidovreDenmarkRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.