NCT05336890Recruiting
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic measures are lacking. This study wants to learn if these problems are related to certain patterns of breathing that babies had while they were in the NICU.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 14 Apr 2022
- Start date
- 1 Nov 2022
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Diseases
- Asthma
- NCT number
- NCT05336890
What you commit to
- Study type: Observational
- Planned participants: 500
- From 1 Nov 2022 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Parent refused further contact, prior to approach for Post-Vent
Other
- Subject was withdrawn from the Pre-Vent study after signing Pre-Vent consent form, for any reason
- Subject had no physiological data recorded as part of Pre-Vent
- Lack of regulatory approval from local IRB or Department of Children and Family Services (DCFS) to recontact subjects
- Adopted by non-consenting family
- Infant enrolled in Pre-Vent at Washington University St Louis, which is not a Post-Vent participating site.
Who the study is looking for
- Enrolled in any Institutional Review Board (IRB) protocol of the Pre-Vent Study that had signed consent, or in any IRB protocol of the Pre-Vent Study that authorized re-contact for future research
- Born \<29 weeks gestational age
- Age at enrollment less than 7 years old
Age in the registry: 30 weeks to 83 months · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ann & Robert H. Lurie Children's Hospital of Chicago Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.