NCT05337904Active, not recruiting
Deep Brain Stimulation Recovery in Treatment-Resistant Schizophrenia
Deep Brain Stimulation: Towards a Novel Intervention Focused on the Recovery of Patients With Treatment-Resistant Schizophrenia: Randomized, Controlled, Crossover Pilot Study
Source: ClinicalTrials.gov · Last updated 29 Jul 2025
Brief summary (registry, in English)
The purpose of this project is to improve the clinical response and personal recovery of patients with treatment-resistant schizophrenia (TRS).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 6 (estimated)
- First submitted
- 17 Mar 2022
- Start date
- 1 Sept 2023
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
- Diseases
- Schizophrenia
- NCT number
- NCT05337904
What you commit to
- Study type: Interventional
- Planned participants: 6
- From 1 Sept 2023 to the primary completion date, 1 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Epilepsy or seizures clozapine-induced
- Other psychiatric disorders (including personality disorders)
- Significant cognitive impairment (Vocabulary test WAIS IV-TR, IQ \<70, and SCIP\<55)
- Severe medical non-controlled diseases
- Substance use disorders (except nicotine)
Other
- Contraindications to neurosurgery or DBS
- Suicidal or self-harming behaviour in the last 6 months
- Pregnancy or breastfeeding
Who the study is looking for
- Individuals aged 18-50 years
- Meet DSM-5 criteria for schizophrenia, with a duration of illness \< than 15 years.
- Meet updated TRS criteria.
- Non-sustained response to electroconvulsive therapy.
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Psychiatry. Hospital Santa Creu i Sant Pau Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.