NCT05340686Suspended
Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression
Braining - A Randomized Controlled Study on Moderate-vigorous Aerobic Physical Exercise (PE) as an add-on Treatment in Bipolar Disorder. Effects on Recovery Time and Long-term Prevention From Bipolar Depression
Source: ClinicalTrials.gov · Last updated 10 Feb 2026
Reason given: Difficulties recruiting
Brief summary (registry, in English)
Hypothesis: the hypothesis of the study is that aerobic physical exercise (PE) performed with the method Braining accelerates recovery from bipolar depression as well as improves psychiatric and somatic health in individuals with bipolar depression Method: a randomized controlled trial with 54 patients with bipolar depression are randomized to 6 weeks of either 1) supervised aerobic PE 3 times/week, 2) supervised relaxation/stretching 3 times/week or 3) information about PE but no supervised activity.
- Status (registry)
- Suspended
- Study type
- Interventional
- Enrollment
- 54 (estimated)
- First submitted
- 31 Mar 2022
- Start date
- 26 Oct 2022
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Region Stockholm
- Diseases
- Bipolar disorder
- NCT number
- NCT05340686
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe psychiatric disorder such as mania and psychosis
- Medical conditions such as heart- and lung diseases where PE is contraindicated.
Other
- Unable to understand written and spoken Swedish language.
Who the study is looking for
- Patients at Psychiatry Southwest, Karolinska University Hospital Region Stockholm Sweden.
- Bipolar disorder
- Ongoing depression, defined as a PHQ-9 score of 9 or higher at any occasion 2 weeks before inclusion.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Region Stockholm, Psykiatri Sydväst (Psychiatric Clinic Psychiatry Southwest) | Stockholm | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.