NCT05341453Completed
Equine-Assisted Physiotherapy for Spinal Muscular Atrophy
Immediate and Sustained Effects of Intensive Equine-Assisted Physiotherapy in Children With Spinal Muscular Atrophy
Source: ClinicalTrials.gov · Last updated 28 Jul 2026
Brief summary (registry, in English)
This prospective interventional study evaluates the immediate and sustained effects of intensive equine-assisted physiotherapy in children with spinal muscular atrophy (SMA). The study compares an intensive equine-assisted physiotherapy program (NEUROEQUIP-SMA) with an individualized physiotherapy program based on SMA standard of care and neuroproprioceptive facilitation and inhibition principles (SMA-SOC-N). Both interventions are delivered as intensive 6-day rehabilitation programs. Outcomes include motor function, postural control, respiratory function, movement quality assessed by three-dimensional motion analysis, neuromuscular activity, quality of life, and selected molecular biomarkers. The study also evaluates the safety and tolerability of intensive rehabilitation in children with SMA.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 21 (actual)
- First submitted
- 18 Apr 2022
- Start date
- 22 Apr 2022
- Primary completion date
- 25 Sept 2024
- Lead sponsor
- Charles University, Czech Republic
- Diseases
- Spinal muscular atrophy
- NCT number
- NCT05341453
What you commit to
- Study type: Interventional
- Participants enrolled: 21
- From 22 Apr 2022 to the primary completion date, 25 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- allergies to horses and the environment of horse stables
Other
- hip luxation
- insurmountable fear of the horse
Who the study is looking for
- clinic diagnosis SMA (I, II, and III types)
- no changing medicine 6 months at least
- without another grave diseases
Age in the registry: 1 year to 10 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kamila Řasová Coordinator of this site? Confirm its status | Prague | Czechia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.