NCT05345613RecruitingPhase 4
Tranexamic Acid During Colonic Endoscopic Resection Procedures
Usage of Tranexamic Acid During Colonic Endoscopic Resection Procedures for Reduction Intraprocedural and Postprocedural Bleeding
Source: ClinicalTrials.gov · Last updated 13 Jan 2026
Brief summary (registry, in English)
Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on preventing intraprocedural and postprocedural bleeding in patients undergoing endoscopic mucosal resection (EMR) of large colon polyps.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 10 Apr 2022
- Start date
- 1 May 2022
- Primary completion date
- 1 Sept 2026
- Lead sponsor
- Assaf-Harofeh Medical Center
- Diseases
- Colorectal cancer
- NCT number
- NCT05345613
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 200
- From 1 May 2022 to the primary completion date, 1 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- patients with histories of allergic reactions to TXA
- history of seizures
Other
- pregnancy
Who the study is looking for
- Patients referred for endoscopic resection of non-neoplastic and neoplastic lesions in the colon presenting to our tertiary academic center.
- Age \> 18 years
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shamir Medical Center Coordinator of this site? Confirm its status | Be’er Ya‘aqov | Israel | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.