NCT05346380CompletedPhase 1/2
Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download
Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery
Source: ClinicalTrials.gov · Last updated 26 Nov 2025
Brief summary (registry, in English)
This will be a prospective, (NSR), single-center feasibility study of the Olympus VE2 NIR Imaging System to assess perfusion using NIR during minimally invasive esophagectomy and pulmonary segmentectomy. The aims of the study are: 1\. To utilize NIR intraoperative imaging with the Olympus VE2 NIR Imaging System to: i. Characterize gastric conduit perfusion during esophagectomy and, ii. Identify segmental anatomy during sublobar pulmonary resection (segmentectomy) after intraoperative, intravenous delivery of low-dose 0.15 mg/kg of ICG.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 38 (actual)
- First submitted
- 11 Feb 2022
- Start date
- 29 Oct 2020
- Primary completion date
- 3 Jun 2025
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Lung cancer, Childhood cancers
- NCT number
- NCT05346380
What you commit to
- Study type: Interventional · Phase 1/2
- Participants enrolled: 38
- From 29 Oct 2020 to the primary completion date, 3 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subject is not eligible for surgical resection as determined by the treating physician
Age
- Subject has known or suspected allergy to Iodine, shellfish or intravenous contrast
- Subject is not eligible or considered high risk for surgical resection as determined by pre-operative spirometry
- Subject is female and of childbearing age who is currently pregnant or who is planning to become pregnant within the study
- Subject is unable and unwilling to provide informed consent
- Subject has liver disease or is taking drugs impact liver metabolism.
Who the study is looking for
- -Subject has a suspicious lung lesion for which a minimally invasive segmentectomy is planned -OR- sub-ject has an esophageal lesion for which an esophagectomy is planned -
- Subject is 18 years of age or older
- Subject is willing and able to provide informed consent
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.