NCT05350553Completed
Methylglyoxal Evaluation in Humans
A Cross-Sectional Trial of Methylglyoxylated-Protein Levels in Adults With Chronic Pain
Source: ClinicalTrials.gov · Last updated 4 Apr 2025
Brief summary (registry, in English)
The investigators will test the hypothesis that patients with low back pain associated with lumbar disc aberrancy will have elevated MGO-protein levels circulating in the blood that are comparable to patients with painful diabetic neuropathy.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 39 (actual)
- First submitted
- 6 Apr 2022
- Start date
- 2 May 2022
- Primary completion date
- 1 Apr 2025
- Lead sponsor
- University of Kansas Medical Center
- Diseases
- Type 2 diabetes
- NCT number
- NCT05350553
What you commit to
- Study type: Observational
- Participants enrolled: 39
- From 2 May 2022 to the primary completion date, 1 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Lumbar surgery due to disc aberrancy
- Therapeutic spinal injections within the last 3 months (steroid, ablations, etc.)
- Chronic use of steroids or non
- steroidal anti-inflammatory drugs (NSAIDS) within 3 months of pre-screen
Other illness
- Current clinically significant cardiac or neurological disease
- Diagnosis of IBS, osteoarthritis, fibromyalgia, complex regional pain syndrome (CRPS), postherpetic neuralgia
Other
- Prisoner
- Past or present use of spinal cord stimulators
Who the study is looking for
- Informed consent provided by the subject
- Able to read/speak English
- TYPE 2 DIABETES
- All healthy inclusion criteria AND
- Blood glucose levels \> 126 mg/dl
- Diagnosed with neuropathy or experience painful numbness or tingling in their hands or feet
- LOW BACK PAIN
- All healthy inclusion criteria AND
- Chronic (persistent pain lasting longer than 3 months) low back pain as a direct result of non-operative lumbar disc aberrancy (disc herniation, protrusion, or extrusion)
- Aberrancy occurring within 12 months of pre-screening
Age in the registry: 45 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Kansas Medical Center Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.