NCT05351242Not yet recruiting
THERMotherapy Against Persistent Bacterial LUNG Infections
Source: ClinicalTrials.gov · Last updated 17 Jun 2026
Brief summary (registry, in English)
The aim of this study is to determine whether an intervention with frequent thermotherapy will be able to reduce the amount of colonizing bacteria in the bronchoalveolar lavage sample and eradicate the colonizing bacteria.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 19 Apr 2022
- Start date
- 1 Oct 2026
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- Chronic Obstructive Pulmonary Disease Trial Network, Denmark
- NCT number
- NCT05351242
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 1 Oct 2026 to the primary completion date, 31 Dec 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous severe laryngospasm (intubation requiring)
Other illness
- Allergy to lidocaine and/or midazolam
- Severe mental illness that is not controlled with medication. NB: Patients with controlled mental illness can be included and will be asked on an equal footing as others
Other
- Contraindications to bronchoscopy
- Pregnancy/breastfeeding
- Severe linguistic problems or inability to give informed consent
Who the study is looking for
- Age ≥ 18 years
- Competent and capable
- FEV1\>1,0 L
- Have had a positive culture from sputum or BAL min. 2 times in the last 24 months for bacteria of the species: Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Staphylococcus aureus, Haemophilus influenzae, Achromobacter xylosoxidans, Klebsiella oxytoca or Klebsiella pneumoniae. In addition, min. 1 positive culture after treatment with antibiotics
- Willing to go to a sauna (min. temperature of 85℃ for at least 7 minutes) four times weekly for six months or avoid going to a sauna for six months
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Herlev and Gentofte University Hospital Coordinator of this site? Confirm its status | Hellerup | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.