NCT05351515Completed
Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography
Source: ClinicalTrials.gov · Last updated 20 Oct 2026
Brief summary (registry, in English)
Obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) are both common diseases related to metabolic diseases with potential cardiovascular consequences and liver complications respectively. Though studies show OSA may take part in the progression of hepatic steatosis, the independent contribution of OSA on liver fat accumulation is unknown. It is hypothesized that nocturnal intermittent hypoxia from OSA is the main driver of NAFLD in non-obese OSA patients. This study is to assess the effect of OSA on NAFLD in non-obese patients.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 861 (actual)
- First submitted
- 14 Apr 2022
- Start date
- 10 Jan 2022
- Primary completion date
- 10 Nov 2025
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Obesity, Fatty liver disease (MASLD/MASH)
- NCT number
- NCT05351515
What you commit to
- Study type: Observational
- Participants enrolled: 861
- From 10 Jan 2022 to the primary completion date, 10 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- secondary causes of hepatic steatosis (such as chronic use of systemic corticosteroids)
- positive hepatitis B surface antigen, anti-hepatitis C virus antibody, or histological evidence of other concomitant chronic liver diseases.
Other illness
- underlying cause of liver disease
- history of excessive alcoholic consumption (more than 30 g/day for men and 20 g/day for women)
Who the study is looking for
- aged 18 years or more
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chinese University of Hong Kong Coordinator of this site? Confirm its status | Hong Kong | Hong Kong | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.