NCT05356923Completed
PROFILE-MI - The FAPI Fibrosis Study
PROline and FapI With Late Gadolinium Enhancement in Myocardial Infarction PROFILE-MI - The FAPI Fibrosis Study
Source: ClinicalTrials.gov · Last updated 17 May 2024
Brief summary (registry, in English)
The investigators here propose to investigate the timing and pattern of myocardial fibrosis activity following acute myocardial infarction using hybrid 68Ga-FAPI positron emission tomography and cardiovascular magnetic resonance. The investigators hypothesise that peak fibrosis activity will occur within 2-4 weeks of acute myocardial infarction and will predict subsequent scar formation and cardiac remodelling. Simultaneously, matrix remodelling and fibrosis activity in aortic and coronary atheroma will be assessed enabling the exploration of the presence of unstable atheroma.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 26 Apr 2022
- Start date
- 21 Apr 2021
- Primary completion date
- 31 Dec 2023
- Lead sponsor
- University of Edinburgh
- Diseases
- Coronary artery disease
- NCT number
- NCT05356923
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 21 Apr 2021 to the primary completion date, 31 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- eGFR \<30ml/min/1.73\^m2
Other
- Claustrophobia
- Inability to undergo MRI
Who the study is looking for
- specific to cohort;
- aged 50 years or older
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Infirmary of Edinburgh Coordinator of this site? Confirm its status | Edinburgh | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.