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NCT05356923Completed

PROFILE-MI - The FAPI Fibrosis Study

PROline and FapI With Late Gadolinium Enhancement in Myocardial Infarction PROFILE-MI - The FAPI Fibrosis Study

Source: ClinicalTrials.gov · Last updated 17 May 2024

Brief summary (registry, in English)

The investigators here propose to investigate the timing and pattern of myocardial fibrosis activity following acute myocardial infarction using hybrid 68Ga-FAPI positron emission tomography and cardiovascular magnetic resonance. The investigators hypothesise that peak fibrosis activity will occur within 2-4 weeks of acute myocardial infarction and will predict subsequent scar formation and cardiac remodelling. Simultaneously, matrix remodelling and fibrosis activity in aortic and coronary atheroma will be assessed enabling the exploration of the presence of unstable atheroma.

Status (registry)
Completed
Study type
Observational
Enrollment
80 (actual)
First submitted
26 Apr 2022
Start date
21 Apr 2021
Primary completion date
31 Dec 2023
Lead sponsor
University of Edinburgh
NCT number
NCT05356923

What you commit to

  • Study type: Observational
  • Participants enrolled: 80
  • From 21 Apr 2021 to the primary completion date, 31 Dec 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Lab values

  • eGFR \<30ml/min/1.73\^m2

Other

  • Claustrophobia
  • Inability to undergo MRI

Who the study is looking for

  • specific to cohort;
  • aged 50 years or older

Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Royal Infirmary of Edinburgh
Coordinator of this site? Confirm its status
EdinburghUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.