NCT05359068CompletedPhase 3
Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension
A Multi-center, Randomized, Double-blind, Double-Dummy, Positive Parallel Controlled Study to Evaluate the Efficacy and Safety in Treatment of Mild-moderate Essential Hypertension
Source: ClinicalTrials.gov · Last updated 7 May 2024
Brief summary (registry, in English)
The primary aim of the study is to assess the antihypertensive efficacy of SPH3127 in patients with mild to moderate essential hypertension.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 957 (actual)
- First submitted
- 27 Apr 2022
- Start date
- 10 Jun 2021
- Primary completion date
- 26 Dec 2023
- Lead sponsor
- Shanghai Pharmaceuticals Holding Co., Ltd
- Diseases
- High blood pressure
- NCT number
- NCT05359068
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 957
- From 10 Jun 2021 to the primary completion date, 26 Dec 2023
- 40 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subject is planning or in use of other antihypertensive drugs or other drugs may affect blood pressure during the trial;
- Alcohol or drug abuse;
Other illness
- Diagnosed with secondary hypertension, suspected grade 3 hypertension, acute hypertension, or at risk when current antihypertensive therapy discontinued;
- Suffered by severe heart disease within 6 months;
- Suffered by severe cerebrovascular disease within 6 months;
- Suffered by severe or malignant retinopathy;
- Out of controlled diabetes;
- History of malignant tumor;
- History of mental disorder;
Other
- Pregnant, lactating women or subject is planning to pregnant within 6 months after the trial;
- Assessed by the investigators as unsuitable for participating in the study.
Who the study is looking for
- Male or female of age ≥18 years;
- Diagnosed with mild-moderate essential hypertension;
- Participant has understood the study-required procedures, voluntarily signed informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (40)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology Coordinator of this site? Confirm its status | Baotou | China | Unknown status |
| Beijing Anzhen Hospital, Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| Beijing Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| Beijing Pinggu Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| Cangzhou Central Hospital Coordinator of this site? Confirm its status | Cangzhou | China | Unknown status |
| XiangYa Hospital CentralSouth University Coordinator of this site? Confirm its status | Changsha | China | Unknown status |
| The Second Xiangya Hospital of Central South University Coordinator of this site? Confirm its status | Changsha | China | Unknown status |
| The Third Xiangya Hospital of Central South University Coordinator of this site? Confirm its status | Changsha | China | Unknown status |
| West China Hospital,Sichuan University Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| Chifeng Municipal Hospital Coordinator of this site? Confirm its status | Chifeng | China | Unknown status |
| Affiliated Hospital of Chongqing Three Gorges Medical College Coordinator of this site? Confirm its status | Chongqing | China | Unknown status |
| Guangdong Second Provincial General Hospital Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
| Guangdong Provincial People's Hospital Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
| Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
| Zhejiang Provincial People's Hospital Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
| The Affiliated Hospital of Inner Mongolia Medical University Coordinator of this site? Confirm its status | Hohhot | China | Unknown status |
| Lanzhou University Second Hospital Coordinator of this site? Confirm its status | Lanzhou | China | Unknown status |
| Liuzhou People's Hospital Coordinator of this site? Confirm its status | Liuzhou | China | Unknown status |
| Luoyang Third People's Hospital Coordinator of this site? Confirm its status | Luoyang | China | Unknown status |
| The Second Affiliated Hospital of Nanjing Medical University Coordinator of this site? Confirm its status | Nanjin | China | Unknown status |
| The First Affiliated Hospital with Nanjing Medical University Coordinator of this site? Confirm its status | Nanjing | China | Unknown status |
| Hainan Third People's Hospital Coordinator of this site? Confirm its status | Sanya | China | Unknown status |
| Ruijin Hospital Shanghai Jiaotong University School of Medicine Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
| The People's Hospital of Liaoning Province Coordinator of this site? Confirm its status | Shenyang | China | Unknown status |
| Shengjing Hospital Of China Medical University Coordinator of this site? Confirm its status | Shenyang | China | Unknown status |
| The Third Hospital of Hebei Medical University Coordinator of this site? Confirm its status | Shijiazhuang | China | Unknown status |
| The First Hospital of Hebei Medical University Coordinator of this site? Confirm its status | Shijiazhuang | China | Unknown status |
| Suzhou Municipal Hospital Coordinator of this site? Confirm its status | Suzhou | China | Unknown status |
| Tianjin Fourth Central Hospital Coordinator of this site? Confirm its status | Tianjin | China | Unknown status |
| People's Hospital of Tianjin Coordinator of this site? Confirm its status | Tianjin | China | Unknown status |
| The First Affiliated Hospital of Xinjiang Medical University Coordinator of this site? Confirm its status | Ürümqi | China | Unknown status |
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Coordinator of this site? Confirm its status | Wuhan | China | Unknown status |
| Tongji Hospital Tongji Medical College of Hust Coordinator of this site? Confirm its status | Wuhan | China | Unknown status |
| Xuzhou Central Hospital Coordinator of this site? Confirm its status | Xuzhou | China | Unknown status |
| The affiliated hospital of xuzhou medical university Coordinator of this site? Confirm its status | Xuzhou | China | Unknown status |
| The First People's Hospital of Yinchuan Coordinator of this site? Confirm its status | Yinchuan | China | Unknown status |
| General Hospital of Ningxia Medical University Coordinator of this site? Confirm its status | Yinchuan | China | Unknown status |
| Yuncheng Central Hospital Coordinator of this site? Confirm its status | Yuncheng | China | Unknown status |
| Henan Provincial People's Hospital Coordinator of this site? Confirm its status | Zhengzhou | China | Unknown status |
| Affiliated Hospital of Jiangsu University Coordinator of this site? Confirm its status | Zhenjiang | China | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.