Colorectal Cancer Screening in Cystic Fibrosis

Prior treatment

• Active inflammatory bowel disease as defined by a prior diagnosis of Crohn's Disease or Ulcerative Colitis, based on both clinical and histopathologic findings and the individual currently on medical therapy for Crohn's disease or Ulcerative Colitis.
• Known history of familial colon cancer syndrome that has been confirmed by previous genetic testing

Other illness

• Any condition that, in the opinion of the site PI, introduces undue risk by participating in this study
• Personal history of colon cancer diagnosis and treatment within 5 years of enrollment

Other

• Incapable of understanding the purposes of the study or informed consent for any reason
• Pregnancy
• Symptoms that merit colonoscopy for diagnostic purposes rather than as screening for CRC

• Adults with CF ages 18 - 75 years and due for a routine screening or surveillance colonoscopy for colon cancer
• Cystic Fibrosis diagnosis, defined by a sweat chloride test result ≥ 60 mmol/L (may be of historic value), and/or documented CF-causing CFTR mutations and clinical features of CF
• Capable of understanding the purposes and risks of the study in English or Spanish and willing to participate and sign informed consent
• Referred for screening or surveillance colonoscopy for CRC (current standard of care) and willing to undergo colonoscopy and stool testing
• Able to access the Internet to complete self-administered surveys