NCT05368545Completed
Influence of Lipid Lowering on Impaired Coronary Flow
Influence of Intensive Lipid-lowering Witgh Statin and Ezetimibe Prescription on Computed Tomography Derived Fractional Flow Reserve in Patients With Stable Chest Pain
Source: ClinicalTrials.gov · Last updated 3 Apr 2025
Brief summary (registry, in English)
This study assess in patients with stable chest pain and coronary artery disease (CAD) determined by coronary CTA whether cholesterol lowering with regression of coronary adverse plaque characteristics is associated with recovery of impaired flow
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 109 (actual)
- First submitted
- 6 May 2022
- Start date
- 15 May 2020
- Primary completion date
- 17 Apr 2024
- Lead sponsor
- Aarhus University Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT05368545
- EudraCT number
- 2019-001912-50
What you commit to
- Study type: Interventional
- Participants enrolled: 109
- From 15 May 2020 to the primary completion date, 17 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergy to ionidated contrast
Other
- Known CAD
- Poor CTA image quality inadequiate for FFRct analysis (determined by corelab)
- Significant CAD in the left main or proximal coronary segments
- Referral to invasive catheterization
- Statin intolerance
- BMI \>40
- Pregnancy
Who the study is looking for
- Age ≥35 y
- Symptoms suggestive of stable CAD
- No pre-CTA known CAD
- At least one lesion with FFRct \<0.81
- Sinus rhythm
- LDL cholesterol \>2.0 mM
- Statin use \>2 months
- Life expentancy \< 3 years
- Signed informed consent
Age in the registry: 35 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.