NCT05369234CompletedPhase 3
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis: a Single-blind Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 10 Oct 2024
Brief summary (registry, in English)
As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. The intention is to determine whether aloe vera juice should be considered as part of standard treatment.
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 28 Apr 2022
- Start date
- 20 Jan 2022
- Primary completion date
- 30 Jan 2024
- Lead sponsor
- Covenant Health Cancer Center
- NCT number
- NCT05369234
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 100
- From 20 Jan 2022 to the primary completion date, 30 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are not on concurrent chemotherapy and radiation.
Other illness
- History of allergic reactions attributed to compounds of similar chemical or biologic composition to aloe vera juice.
- Patients with psychiatric illness/social situations that would limit compliance with study requirements.
Other
- Pregnant women or women who are breastfeeding
Who the study is looking for
- must have signed and dated an IRB approved consent form that conforms to federal and institutional guidelines
- Age \>/= 18 years
- Confirmed lip, oral cavity, hard palate, tongue, tonsil, pharyngeal, neck, esophageal, mediastinal, and/or chest wall cancers
- Women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation.
- Men treated or enrolled on this protocol must agree to use adequate contraception prior to the study, for the duration of study participation.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Thompson Cancer Survival Center Radiation Oncology Services Coordinator of this site? Confirm its status | Knoxville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.