NCT05369416Active, not recruiting
Renal Metabolism in Salt-sensitive Human Blood Pressure
Source: ClinicalTrials.gov · Last updated 13 Nov 2025
Brief summary (registry, in English)
Salt sensitive hypertension is a significant health problem worldwide and a primary modifiable risk factor for renal, cardiovascular, and cerebrovascular diseases. Yet, the underlying mechanisms remain poorly understood. The proposed study determines how renal oxygenation and substrate metabolism differs between individuals with and without salt sensitivity, with the ultimate goal of identifying mechanisms, diagnostic criteria, and treatment strategies for salt sensitive hypertension.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 6 May 2022
- Start date
- 1 Nov 2021
- Primary completion date
- 30 Jan 2030
- Lead sponsor
- Medical College of Wisconsin
- Diseases
- High blood pressure
- NCT number
- NCT05369416
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 1 Nov 2021 to the primary completion date, 30 Jan 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of pacemaker or other metallic implants
Other illness
- H/o diabetes, congestive heart failure, cirrhosis of the liver, hypokalemia \& other
- H/o kidney disease
- Presence of bleeding disorders
- Allergy to iodinated contrast
- Allergy to shellfish
Lab values
- Use of anti-platelet and anticoagulant agents such as clopidogrel, aspirin, dabigatran, rivaroxaban etc
- Daily sodium intake ≥ 6000 mg/day
Other
- Non-English speakers
- BP ≤120/80 \& ≥ 140/90 mmHg
- electrolyte disturbances
- Use of glucocorticoids
- Pregnant or nursing mothers
- Claustrophobia
Who the study is looking for
- English speaking subjects
- With a spectrum of BPs, ranging from those with Elevated BP through Stage 1 HTN, as defined by the 2017 ACC/AHA HTN guidelines
Age in the registry: 30 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical College of Wisconsin/ Froedtert Hospital Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.