NCT05374109Completed
SYV: A Mental Health Intervention to Improve HIV Outcomes in Tanzanian Youth
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
The overall objectives of this proposal are to support positive coping strategies that bolster mental health and lead to improved HIV outcomes among Young People Living with HIV (YPLWH). The central hypothesis is that SYV (Sauti ya Vijana, The Voice of Youth) will be effective to improve antiretroviral therapy (ART) adherence and virologic suppression in YPLWH in Tanzania. The rationale for this project is that by targeting mental health, which is strongly associated with medication adherence, that this will effectively improve adherence and thereby HIV viral suppression. The central hypothesis will be tested in three aims in a hybrid type-1 effectiveness-implementation trial.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 690 (actual)
- First submitted
- 6 May 2022
- Start date
- 1 Mar 2023
- Primary completion date
- 20 Dec 2024
- Lead sponsor
- Duke University
- Diseases
- HIV
- NCT number
- NCT05374109
What you commit to
- Study type: Interventional
- Participants enrolled: 690
- From 1 Mar 2023 to the primary completion date, 20 Dec 2024
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Active psychosis
- Developmental delay, or cognitive disability that precludes active participation in consent process, intervention, and assessment interviews
Who the study is looking for
- Youth between the ages of 10 and 24 years of age
- Attending the enrolling adolescent HIV clinic
- Are fully disclosed and aware of their HIV status
- Receiving ART for a minimum of 6 months
- If ≥ 18 years, able to understand the project and provide written informed consent
- If \<18 years, a parent or guardian must provide written permission and participant must be able to assent
- All adolescents must also commit to attending the 10 weekly SYV sessions and 2 individual sessions
Age in the registry: 10 years to 24 years · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chronic Disease Clinic of Ifakara Health Institute Coordinator of this site? Confirm its status | Ifakara | Tanzania | Unknown status |
| Baylor College of Medicine Children's Foundation - Tanzania, Mbeya Centre for Excellence Coordinator of this site? Confirm its status | Mbeya | Tanzania | Unknown status |
| Kilimanjaro Christian Medical Centre Coordinator of this site? Confirm its status | Moshi | Tanzania | Unknown status |
| Mawenzi Regional Referral Hospital Coordinator of this site? Confirm its status | Moshi | Tanzania | Unknown status |
| Baylor College of Medicine Children's Foundation - Tanzania, Mwanza Centre for Excellence Coordinator of this site? Confirm its status | Mwanza | Tanzania | Unknown status |
| Bugando Medical Centre Coordinator of this site? Confirm its status | Mwanza | Tanzania | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.