NCT05374642Completed
Atrial Fibrillation Follow-up Investigation to Recover Memory and learnING Trial
Randomized Controlled Trial of Computerized Cognitive Training in Patients With Atrial Fibrillation With Cognitive Impairment But Without Dementia
Source: ClinicalTrials.gov · Last updated 24 May 2024
Brief summary (registry, in English)
The objective of the study is to evaluate the effectiveness of cognitive training in people with atrial fibrillation and cognitive decline over 12-week cognitive training. Moreover, the investigators will explore whether the training effect can be maintained.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 10 May 2022
- Start date
- 19 Sept 2022
- Primary completion date
- 22 Dec 2023
- Lead sponsor
- Beijing Anzhen Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT05374642
What you commit to
- Study type: Interventional
- Participants enrolled: 200
- From 19 Sept 2022 to the primary completion date, 22 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Alcohol abuse or taking drugs that affect cognitive function (antihistamines, antipsychotics);
- Planned atrial fibrillation ablation within 3 months or received ablation in the last 3 months;
- Previous neurosurgery or a history of head tumor;
Other illness
- Dementia or MMSE Scale ≤ 20;
- A history of stroke and head injury in the last 6 months;
- Past history of Parkinson's disease, schizophrenia, and epilepsy;
Other
- Unable to complete the test due to vision, hearing and other problems;
- Cannot master the method of cognitive training tool after 2 times, 1 hour each time training instruction;
- CHA2DS2-VASc score ≥ 2 (for female ≥ 3), but refuses anticoagulation or has anticoagulation contraindications;
- General anaesthesia in the last 3 months;
- Contraindications for MRI examination: such as metal implantation, claustrophobia, etc.;
- No family members to assist the patients to do the training course
Who the study is looking for
- Older than 18 years;
- Completion of 6 or more years of education;
- Atrial fibrillation confirmed by ECG ;
- Complain of memory decline within 1 year;
- The score of any cognitive domain in the processing speed, episodic memory, working memory, and visual-spatial tested by the Basic Cognitive Ability Assessment (BCAT) is 1SD less than the average of the normal population;
- Agree to receive cognitive function testing and randomization, be able to receive follow-up as required
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beijing Anzhen Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.