NCT05380622Recruiting
CHART Study of Coronary CT Angiography in Coronary Artery Disease
CHART Study of Coronary CT Angiography to Predict Imaging and Cardiovascular Outcomes in Patients With Coronary Artery Disease
Source: ClinicalTrials.gov · Last updated 25 May 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
In a cohort of patients referred to coronary computed tomography angiography (CCTA), the investigators aim: 1. To describe the natural history of the coronary atherosclerotic plaque development and progression or regression, as well as the plaque characterization and phenotypes over time by CCTA among deferred coronary lesions 2. To explore the precursors of plaques leading to acute coronary syndrome (ACS) or chronic coronary syndrome (CCS) in deferred coronary lesions 3. To investigate prognostic implication of qualitative and quantitative plaque analysis of stenosis and plaque features, disease patterns, hemodynamic parameters, and fat metrics on CCTA along with physiologic assessment 4. To investigate the effects of different treatment strategies according to stenosis and plaque features, fat metrics on CCTA along with physiologic assessments.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 5000 (estimated)
- First submitted
- 10 May 2022
- Start date
- 1 Jan 2015
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- Shanghai Zhongshan Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT05380622
What you commit to
- Study type: Observational
- Planned participants: 5000
- From 1 Jan 2015 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Acute ST-elevation myocardial infarction within 72 hours or previous coronary artery bypass graft surgery
- Planned coronary artery bypass graft surgery after diagnostic angiography
Lab values
- Left ventricular ejection fraction \< 35%
Other
- Abnormal epicardial coronary flow (TIMI flow \< 3)
- Poor quality of CCTA or other reasons by core lab that are unsuitable for plaque, physiological or fat analysis
- Patients with a stent in the target vessel
Who the study is looking for
- Patients with an indication for CCTA.
- Qualified patients who have signed a written informed consent form.
Age in the registry: 18 years to - · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shanghai Zhongshan Hospital Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.