NCT05404867Completed
Study of Structural and Functional Brain Connectivity Changes in ALS (CoALS-II)
Source: ClinicalTrials.gov · Last updated 9 Jan 2024
Brief summary (registry, in English)
This study will try to understand the difference in brain structure between ALS patients and healthy people of similar age. ALS is a condition affecting the nervous system with disruption of the brain networks. This study aims to understand these disruptions and determine their significance in ALS.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 31 (actual)
- First submitted
- 31 May 2022
- Start date
- 8 Jun 2022
- Primary completion date
- 30 Jun 2023
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT05404867
What you commit to
- Study type: Interventional
- Participants enrolled: 31
- From 8 Jun 2022 to the primary completion date, 30 Jun 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \<18
Other
- Unable to undergo MRI due to any reason
- ALS patients having high aspiration risk
- Patients having cognitive limitations which prevents them from understanding the study requirements, providing consent or perform tasks inside the scanner.
Who the study is looking for
- Based on El Escorial Criteria we will select Probable or Definite ALS.
- Healthy controls age matched to ALS patients
- Subjects should be able to lie down in a scanner and undergo an hour-long MRI study
- Subjects should be able to understand instructions, provide consent and perform a hand task while inside the scanner
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dartmouth Hitchcock Medical Center Coordinator of this site? Confirm its status | Lebanon | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.