Fact CheckerSign in

NCT05408728Enrolling by invitation

Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome

Dietary Sugar Hyper-absorptive Intestinal Phenotype as a Predictor of Weight Loss Post-bariatric Surgery

Source: ClinicalTrials.gov · Last updated 2 Oct 2026

Brief summary (registry, in English)

This study is trying to determine whether the success of bariatric surgery can be predicted by evaluating the dietary sugar absorptive characteristics in the small intestine and if there is any gene expression change on the dietary sugar absorptive characteristics.

Status (registry)
Enrolling by invitation
Study type
Observational
Enrollment
52 (estimated)
First submitted
2 Jun 2022
Start date
1 Jul 2026
Primary completion date
Aug 2028
Lead sponsor
Mayo Clinic
Diseases
Obesity
NCT number
NCT05408728

What you commit to

  • Study type: Observational
  • Planned participants: 52
  • From 1 Jul 2026 to the primary completion date, Aug 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Pregnant women because endoscopy is a risk factor. All patients of childbearing age undergo history as well as urine pregnancy test as a standard of care prior to undergoing endoscopy as the procedure is performed under anesthesia.
  • Using weight loss medications.

Other illness

  • Subjects with preexisting conditions (e.g., bleeding at the time of the procedure, suspected perforation during the standard-of-care procedure) will be excluded from the study at the time of the endoscopy.
  • A history of surgery on the stomach or small intestine.
  • Type 1 diabetes (clinical diagnosis and/or positive glutamic acid decarboxylase antibodies).
  • Active malignancy within the last 5 years.

Other

  • Adults unable to consent, including non-English speakers.
  • Prisoners.
  • Have a contraindication to endoscopy.

Who the study is looking for

  • \- Obese patients (BMI ≥ 30) scheduled for BS undergoing standard of care screening EGD, or lean BS-naïve individuals (BMI ≤ 25) subjected to EGD for routine clinical indications as part of standard care.

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Mayo Clinic Florida
Coordinator of this site? Confirm its status
JacksonvilleUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.