NCT05410353Active, not recruiting
Choosing Healthy Activities and Lifestyle Management Through Portal Support
Managing Obesity by Leveraging Health Information Technology to Lower Cancer Risk
Source: ClinicalTrials.gov · Last updated 20 Nov 2025
Brief summary (registry, in English)
The study aims to randomize 250 participants to 1 of 2 arms: a.) an Active Intervention Group (based on the Look AHEAD\* ILI) or b.) a Comparison Group (based on the Look AHEAD DSE Comparison group) to test the hypothesis that a multicomponent, multilevel behavioral weight loss intervention (Active Intervention Group) adapted for different population groups and delivered through Health Information Technology (Health IT) tools via the Electronic Health Record (EHR) patient portal, will result in significantly greater weight loss 12 months after enrollment compared to the Comparison Group. \*The Look AHEAD study was a multi-center, randomized clinical trial involving overweight and obese persons with type 2 diabetes, aimed to determine the effects on the cardiovascular outcomes of an intensive lifestyle intervention (ILI) for weight loss, in comparison to the diabetes support and education intervention (DSE).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 229 (actual)
- First submitted
- 25 May 2022
- Start date
- 24 Feb 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of Tennessee
- Diseases
- Obesity, Childhood cancers
- NCT number
- NCT05410353
What you commit to
- Study type: Interventional
- Participants enrolled: 229
- From 24 Feb 2023 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- current weight loss medication use
Other illness
- coronary or cerebrovascular disease events or vascular procedures within the past 6 months
- certain medical conditions that put participants at high risk of adverse events or preclude exercising
- uncontrolled psychiatric disorders
- a history of amputation or bariatric surgery or are planning to have bariatric surgery within the next 12 months
- malignancy within the last 5 years (except skin cancer)
Other
- current substance abuse, including heavy alcohol use ≥ 5 drinks on the same occasion for ≥ 5 days in the past 30 days
- plans to move out of the area during the next year
- current participation in another clinical trial
- pregnancy or breast feeding or are planning to become pregnant within the next 12 months, and
- instances judged by the investigators' and primary care providers' discretion.
Who the study is looking for
- are ≥ 16 years old
- are overweight or obese (BMI ≥ 25 kg/m2)
- have access to the Internet via the computer or use a cellphone with a data-plan access
- are patients at one of the participating practice sites
- are willing to accept a random assignment, and
- are from different population groups (racial / ethnic minority, lower socioeconomic status, or reside in a rural location).
Age in the registry: 16 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Tennessee Health Science Center / Department of Preventive Medicine Coordinator of this site? Confirm its status | Memphis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.