NCT05412394RecruitingPhase 4
Once Weekly Infant Corticosteroid Trial for DMD
Phase-2 Trial of 5mg/kg/Week Prednisolone in Young Boys With DMD
Source: ClinicalTrials.gov · Last updated 14 Aug 2026
Brief summary (registry, in English)
The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg/kg/week) will be equally effective to the 10mg/kg/week dose.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 26 (estimated)
- First submitted
- 2 Feb 2022
- Start date
- 30 Apr 2021
- Primary completion date
- 31 Aug 2028
- Lead sponsor
- Anne M. Connolly
- Diseases
- Duchenne muscular dystrophy
- NCT number
- NCT05412394
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 26
- From 30 Apr 2021 to the primary completion date, 31 Aug 2028
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior treatment with Glucocorticosteroids
Who the study is looking for
- Subjects ages 1 month through 30 months
- Weakness consistent with Duchenne on exam, creatine kinase ≥ 20 times the upper limit of normal, and genetic mutation known to be causative for DMD.
Age in the registry: 1 month to 30 months · Sex: Male · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lurie Children's Hospital of Chicago Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
| University of Cincinnati Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| Nationwide Children's Hospital Coordinator of this site? Confirm its status | Columbus | United States | Recruiting |
| University of Texas, Southwestern Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.