NCT05412862Recruiting
Positive Emotions Following Acute Cardiac Events
A Novel Psychological-behavioral Intervention to Promote Physical Activity After Acute Coronary Syndrome
Source: ClinicalTrials.gov · Last updated 20 Apr 2026
Brief summary (registry, in English)
The focus of this study is to test the efficacy of a 12-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 24 weeks (with interactive, algorithm-driven, goal-focused text messages in the final 12 weeks), compared to post-acute coronary syndrome (ACS) treatment as usual, in a randomized trial of 280 post-ACS patients with low baseline physical activity.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 280 (estimated)
- First submitted
- 25 May 2022
- Start date
- 12 Sept 2022
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT05412862
What you commit to
- Study type: Interventional
- Planned participants: 280
- From 12 Sept 2022 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Medical conditions likely to lead to death within 6 months.
- Inability to participate in physical activity due to another medical condition (e.g., arthritis)
Other
- Cognitive deficits (assessed via a 6-item cognitive screening tool)
- Moderate-severe depression (Patient Health Questionnaire-9 \[PHQ-9\] score ≥15)
- Inability to read, write, or speak in English
- Inability to receive text-messages
- Current participation in another intervention or program that has been designed to promote well-being or physical activity
Who the study is looking for
- ACS (myocardial infarction or unstable angina)
- Suboptimal physical activity (score of \< 6 on the Medical Outcomes study Specific Adherence Scale item related to physical activity)
Age in the registry: 18 years to 95 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.