NCT05420766Completed
Impact of Sleep Duration on Immune Balance in Urban Children With Asthma
Source: ClinicalTrials.gov · Last updated 4 Sept 2026
Brief summary (registry, in English)
Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes both sleep and asthma management. Further, urban children with asthma suffer from altered immune balance, a key biological process contributing to individual differences in asthma morbidity and sleep health. In the proposed research, the researchers will examine the effects of shortened and recovery sleep on immune balance and associated changes in lung function in urban children with allergic asthma through an experimental design.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 83 (actual)
- First submitted
- 2 Jun 2022
- Start date
- 15 May 2022
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- Rhode Island Hospital
- Diseases
- Asthma
- NCT number
- NCT05420766
What you commit to
- Study type: Interventional
- Participants enrolled: 83
- From 15 May 2022 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Inclusion:
- Children 7-11 years old
- Has physician-diagnosed asthma, per parent and pediatrician report
- Meets criteria for current persistent asthma with a current prescription for an asthma controller medicine
- Obtains 9.0-11.0 h of sleep per 24 h day in the past month
- Has a positive allergy skin test performed at the clinic visit
- Resides and attend school in one of the targeted urban areas (Rhode Island: East Providence, North Providence, Providence, Warwick, Cranston, Woonsocket, Central Falls, Pawtucket, Lincoln, Johnston. Massachusetts: Attleboro, North Attleboro, Fall River.
- Has a primary caregiver who speaks English
- Exclusion:
- No asthma diagnosis
- No use of asthma controller medication
- Severe persistent asthma that is poorly controlled
- Diagnosis of additional pulmonary disease or medical condition or immune deficiency disorders
- Use of systemic steroids \<30 days of screening
- Asthma-related emergency department visit and/or asthma-related hospitalization in past 90 days
- Marked developmental delay, psychiatric conditions, academic/behavioral problems, learning disabilities
- Tanner stage 3-5 of pubertal development
- Diagnosed ADHD; Use of stimulants to treat ADHD
- An Apnea-Hypoxia Index \>5 (indicator of sleep disordered breathing)
Age in the registry: 7 years to 11 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rhode Island Hospital Coordinator of this site? Confirm its status | Providence | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.