NCT05424068Completed
Rehabilitation for People With Advanced Cancer
Project 3 - Phase II, Preference Based, Randomized Controlled Trial of Group-Based, In Person Versus Virtual, Cancer Rehabilitation for People With Metastatic / Advanced Breast or Colorectal Cancers
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
The proposed study is a Phase II, feasibility, randomized controlled preference based study. This will be conducted in Vancouver and Toronto and includes breast and colorectal cancers.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 111 (actual)
- First submitted
- 13 Apr 2022
- Start date
- 2 Dec 2022
- Primary completion date
- 30 Jul 2025
- Lead sponsor
- University Health Network, Toronto
- NCT number
- NCT05424068
What you commit to
- Study type: Interventional
- Participants enrolled: 111
- From 2 Dec 2022 to the primary completion date, 30 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Moderate or severe non-cancer pain (\>6 out of 10 on visual analog scale)
- Moderate or severe cancer bone pain (\>Gr 2 bone pain (i.e., moderate pain limiting instrumental ALDs or worse) as measured on CTCAE (see below))
- Known neurological conditions influencing cognition and preventing safe or appropriate engagement with self-management and exercise recommendations (e.g., dementia, traumatic brain injury, or brain metastasis influencing cognition or causing moderate-to-severe motor-sensory-coordination). Best determined by the referring physician or nurse practitioner.
Other
- Wheelchair level community ambulation
- Severe or uncontrolled depressive symptoms (\>20 on PHQ-9)
- Unable to communicate sufficiently in English to complete intervention, questionnaires, and consent.
- Unwillingness to be randomized, participate in a group intervention, or attend individual physical assessments.
- Inability to operate videoconferencing if preference is virtual programming.
Who the study is looking for
- Age 18 years or older
- Diagnosed with locally advanced incurable or metastatic breast or colorectal cancer
- Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
- Fully independent with ambulation and transfers with or without ambulatory assistance
- Palliative Performance score of \>70 (moderate predictive power estimating life expectancy \>6 months)
- Receiving first or second line anti-cancer treatments in the metastatic / incurable setting (a relative proxy for expected survival \>6 months)
- Medical clearance to participate from treating physician
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Princess Margaret Cancer Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.