NCT05428176Active, not recruiting
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors
Leveraging Digital Health Solutions to Reduce Learning and Functional Disparities in Children With Cancer
Source: ClinicalTrials.gov · Last updated 14 Aug 2026
Brief summary (registry, in English)
This clinical trial evaluates a high intensity electronic health (eHealth) intervention program for reducing learning disparities in children with cancer. Most children with leukemia and lymphoblastic lymphoma can be cured due to advancements in diagnosis and treatment. However, because treatments for these conditions target the central nervous system, these children are at increased risk for developing neurocognitive late effects (problems with attention, thinking, learning, and remembering). Fortunately, many survivors do well, but some children continue to struggle with learning and have academic difficulties after their cancer treatments. The purpose of this research study is to see whether providing parents with educational knowledge and parenting tips using videoconferencing and a special website better helps their cancer survivor child in learning and school achievement compared to typical services.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 332 (actual)
- First submitted
- 10 Jun 2022
- Start date
- 10 Sept 2022
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- City of Hope Medical Center
- NCT number
- NCT05428176
What you commit to
- Study type: Interventional
- Participants enrolled: 332
- From 10 Sept 2022 to the primary completion date, 30 Jun 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Child has previously used the IXL online learning program extensively and unwilling to regularly use it again
Other illness
- History of major psychiatric condition (e.g., psychosis) in parent or child
- Severe neurodevelopmental disorder in the child (e.g., down syndrome, intellectual disability)
- Any other condition that would, in the investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures
Other
- Recent or current participation in a behavioral intervention study with a similar focus
- Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)
Who the study is looking for
- Documented informed consent of the participant and/or legally authorized representative
- Assent, when appropriate, will be obtained per institutional guidelines
- Primary participating parent/caregiver is English- or Spanish-speaking (any race/ethnicity)
- Child is aged 6-12 years (yr.) (for the website usability pre-study, child is age 8 - 12 yrs.)
- Child understands English (but can be bilingual)
- Child treated for acute leukemia (e.g., acute lymphoblastic leukemia, acute myelogenous leukemia) or lymphoblastic lymphoma
- Child is in cancer remission and has completed cancer therapies, including maintenance treatment
- Primary participating parent/caregiver has daily contact with the child
- Child is enrolled in school
Age in the registry: 6 years to - · Sex: All · Accepts healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| City of Hope Medical Center Coordinator of this site? Confirm its status | Duarte | United States | Unknown status |
| Childrens Hospital of Los Angeles Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
| Rady Children's Hospital - San Diego Coordinator of this site? Confirm its status | San Diego | United States | Unknown status |
| University of Calif San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.