NCT05432739Recruiting
Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study
Source: ClinicalTrials.gov · Last updated 15 Jun 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
NIMBLE is a prospective study for blood biomarker study of lung nodules alongside analysing data which has been collected routinely as part of patient care. The primary aim of NIMBLE is to assess whether artificial intelligence and machine learning based radiomics approaches can be used to distinguish between benign disease and malignancy in a new lung nodule after a previously treated cancer, and where malignant to differentiate between metastatic recurrence or a new primary lung cancer.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 20 Jun 2022
- Start date
- 7 Apr 2021
- Primary completion date
- 1 Jan 2026
- Lead sponsor
- Royal Marsden NHS Foundation Trust
- Diseases
- Lung cancer
- NCT number
- NCT05432739
What you commit to
- Study type: Observational
- Planned participants: 500
- From 7 Apr 2021 to the primary completion date, 1 Jan 2026
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Active or previous diagnosis of malignancy (within 5 years preceding baseline scan).
- Clinician-suspected or confirmed active or recent COVID-19 infection (less than 4 weeks before CT scan or required blood sampling date).
Other illness
- Active infection (including tuberculosis or fungal infection).
Other
- Inability to give informed consent.
Who the study is looking for
- Patients under active investigation or surveillance for incidental lung nodules
- Age \> 18.
Age in the registry: 18 years to - · Sex: All
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Barking Havering and Redbridge University Hospitals NHS Trust Coordinator of this site? Confirm its status | Goodmayes | United Kingdom | Recruiting |
| Calderdale and Huddersfield NHS Foundation Trust Coordinator of this site? Confirm its status | Huddersfield | United Kingdom | Recruiting |
| Whittington Health NHS Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| University College London Hospitals NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Princess Alexandra Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Royal Marsden Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Guy's and St Thomas' NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
| Northumbria NHS Foundation Trust Coordinator of this site? Confirm its status | Newcastle upon Tyne | United Kingdom | Recruiting |
| Nottinghamshire Healthcare NHS Foundation Trust Coordinator of this site? Confirm its status | Nottingham | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.