NCT05436613Completed
Transcranial Direct Current Stimulation Therapy for Bipolar Depression
Community-based Transcranial Direct Current Stimulation Treatment for Bipolar Depression
Source: ClinicalTrials.gov · Last updated 14 Aug 2025
Brief summary (registry, in English)
Bipolar disorder is a severe and disabling disorder. The course of illness is often progressive but is highly heterogeneous between individuals and within the lifetime for an individual. The most common treatments are medications. However, for many individuals, combinations of medications are often required, and full recovery is infrequent. The novel brain stimulation treatment, transcranial direct current stimulation (tDCS), is a potential first-line treatment for bipolar depression. The present research question is whether tDCS can be provided as a home-based treatment for bipolar depression for adults with bipolar disorder.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 44 (actual)
- First submitted
- 23 Jun 2022
- Start date
- 1 May 2022
- Primary completion date
- 30 May 2024
- Lead sponsor
- University of East London
- Diseases
- Bipolar disorder
- NCT number
- NCT05436613
What you commit to
- Study type: Interventional
- Participants enrolled: 44
- From 1 May 2022 to the primary completion date, 30 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- comorbid psychiatric disorder
- history of epilepsy
Other
- significant risk of suicide or self harm
- any contraindications to tDCS, including implanted electronic medical devices
Who the study is looking for
- diagnosis of bipolar disorder based on DSM-5 criteria
- minimum score of 18 on the MADRS
- being on a stable dosage of mood stabilizing medication for a minimum of two weeks
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of East London Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.