NCT05443347Completed
Activity, Adiposity, and Appetite in Adolescents 2 Intervention
Source: ClinicalTrials.gov · Last updated 12 Feb 2026
Brief summary (registry, in English)
The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents. To do this we will test our working hypothesis that high levels of regular moderate-to-vigorous physical activity (MVPA), as opposed to body weight status, results in a metabolic phenotype consisting of enhanced metabolic function and proper regulation of appetite. We will randomly assigning sedentary overweight/obese adolescents (N=44) to either a control or structured-exercise group for three months.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 31 (actual)
- First submitted
- 17 Jun 2022
- Start date
- 14 Sept 2022
- Primary completion date
- 25 Nov 2024
- Lead sponsor
- Children's Mercy Hospital Kansas City
- Diseases
- Obesity
- NCT number
- NCT05443347
What you commit to
- Study type: Interventional
- Participants enrolled: 31
- From 14 Sept 2022 to the primary completion date, 25 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking medications know to affect metabolism (e.g. thyroid medication, β-blockers, or stimulants).
Other illness
- Restrained eater (\>13 on the restraint section of the three-factor eating questionnaire; Current/past diagnosis of an eating disorder.
- Self-reported medical conditions (including, but not limited to, diabetes, Crohn's disease, etc.) that may affect adherence to the protocol, exercising safely, or alter metabolism
Age
- BMI \<5th percentile or \>99th percentile for age and sex
Other
- Weight not stable
- Gave birth in the past 12 months or \<6 months post-lactation.
- Active (\>60 min/day exercise)
- Not willing to participate in an exercise program
Who the study is looking for
- Tanner Stage III-V, as determined via self-assessment
- Non-smoking
- Not currently involved in any other research study
- No meds that may alter metabolism
- Sedentary (\<60 min/day exercise)
- Willing to participate in an exercise program
Age in the registry: 14 years to 17 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Mercy Kansas City Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.