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NCT05446805Recruiting

Depression and Driving

The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older Adults (Depression and Driving)

Source: ClinicalTrials.gov · Last updated 8 Jun 2026

Brief summary (registry, in English)

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

Status (registry)
Recruiting
Study type
Observational
Enrollment
150 (estimated)
First submitted
3 Jun 2022
Start date
17 Jun 2021
Primary completion date
17 Jun 2027
Lead sponsor
Washington University School of Medicine
NCT number
NCT05446805

What you commit to

  • Study type: Observational
  • Planned participants: 150
  • From 17 Jun 2021 to the primary completion date, 17 Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Less than 65 years of age

Other

  • Not willing to complete blood draw and/or one other biomarker
  • Does not drive a vehicle/ is no longer actively driving

Who the study is looking for

  • Drive on average at least once per week
  • Has a valid driver's license
  • Willing to complete blood draw
  • Willing to complete either lumbar puncture or PET imaging
  • 65 years or older
  • Speaks English

Age in the registry: 65 years to - · Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Washington University School of Medicine
Coordinator of this site? Confirm its status
St LouisUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.