NCT05447650Completed
Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)
Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT): A Multicenter, Randomized, Sham-controlled, Feasibility Device Trial.
Source: ClinicalTrials.gov · Last updated 24 Jun 2025
Brief summary (registry, in English)
Evaluate the safety and efficacy of transpalpebral microcurrent stimulation (MCS) therapy for patients with nonexudative (dry) age-related macular degeneration (AMD).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 95 (actual)
- First submitted
- 29 Jun 2022
- Start date
- 12 Apr 2022
- Primary completion date
- 15 Jun 2025
- Lead sponsor
- i-Lumen Scientific, Inc.
- Diseases
- Macular degeneration
- NCT number
- NCT05447650
What you commit to
- Study type: Interventional
- Participants enrolled: 95
- From 12 Apr 2022 to the primary completion date, 15 Jun 2025
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- History and/or evidence of exudative age-related macular degeneration in either eye
Other
- History and/or evidence of diabetic retinopathy in either eye
- Current tobacco or tobacco-related product use or history within the past 10 years of heavy smoking (on average, more than half a pack of cigarettes per day)
- Central chorioretinal atrophy in the study eye
- Glaucoma in the study eye
Who the study is looking for
- Age ≥50 years.
- Non-exudative age-related macular degeneration defined as AREDS category 3 Intermediate AMD and/or geographic atrophy
- Best-corrected distance visual acuity 20/40 to 20/200 (inclusive) in the study eye, and BCVA 20/100 or better in the fellow eye
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Austin Research Center for Retina Coordinator of this site? Confirm its status | Austin | United States | Unknown status |
| Retina Consultants of Texas Coordinator of this site? Confirm its status | Bellaire | United States | Unknown status |
| Star Retina Coordinator of this site? Confirm its status | Burleson | United States | Unknown status |
| Cumberland Valley Retina Consultants Coordinator of this site? Confirm its status | Chambersburg | United States | Unknown status |
| Erie Retina Research LLC Coordinator of this site? Confirm its status | Erie | United States | Unknown status |
| Texas Retina Associates Coordinator of this site? Confirm its status | Fort Worth | United States | Unknown status |
| Charles Retina Institute Coordinator of this site? Confirm its status | Germantown | United States | Unknown status |
| University Retina and Macula Associates, PC Coordinator of this site? Confirm its status | Lemont | United States | Unknown status |
| Associated Retina Consultants Coordinator of this site? Confirm its status | Phoenix | United States | Unknown status |
| Bay Area Retina Associates Coordinator of this site? Confirm its status | Walnut Creek | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.