NCT05450133Suspended
Hematological Parameters in Axial Spondyloarthritis
Relationship Between Systemic Inflammatory Index and Disease Activity in Axial Spondyloarthritis
Source: ClinicalTrials.gov · Last updated 1 May 2025
Brief summary (registry, in English)
Axial spondyloarthritis is an inflammatory disease characterized by the involvement of the sacroiliac joints and the spine. Disease activity and structural changes are determined by using physical examination, imaging studies, laboratory parameters, and patient-reported indices. Among laboratory studies, Erythrocyte sedimentation rate (ESR) and c-reactive protein (CRP) are the most commonly utilized parameters. However, the level of ESR and CRP are inadequate in demonstrating disease activity and inflammation compared to other diseases. In this study, the investigators aimed to analyze and compare the systemic inflammatory index (SII), which is a hematologic parameter between subjects with radiographic axial spondyloarthritis, non-radiographic axial spondyloarthritis, and healthy controls. Secondarily, the relationship between disease activity and enthesitis score and SII scores in patients with radiographic and non-radiographic axial spondyloarthritis will be investigated.
- Status (registry)
- Suspended
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 4 Jul 2022
- Start date
- 15 Jul 2022
- Primary completion date
- 15 Feb 2026
- Lead sponsor
- Bozyaka Training and Research Hospital
- Diseases
- Ankylosing spondylitis
- NCT number
- NCT05450133
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute/chronic infections
- Presence of other autoimmune diseases
- Diabetes mellitus
- Coronary arterial disease
- Hypertension
- Malignancy
- Hematological diseases
- Liver diseases
- Renal diseases
Other
- Pregnancy/Lactation
Who the study is looking for
- Diagnosed with axial spondyloarthritis according to the ASAS classification criteria
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Izmir Bozyaka Research and Training Hostpital | Izmir | Türkiye | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.