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NCT05450133Suspended

Hematological Parameters in Axial Spondyloarthritis

Relationship Between Systemic Inflammatory Index and Disease Activity in Axial Spondyloarthritis

Source: ClinicalTrials.gov · Last updated 1 May 2025

Brief summary (registry, in English)

Axial spondyloarthritis is an inflammatory disease characterized by the involvement of the sacroiliac joints and the spine. Disease activity and structural changes are determined by using physical examination, imaging studies, laboratory parameters, and patient-reported indices. Among laboratory studies, Erythrocyte sedimentation rate (ESR) and c-reactive protein (CRP) are the most commonly utilized parameters. However, the level of ESR and CRP are inadequate in demonstrating disease activity and inflammation compared to other diseases. In this study, the investigators aimed to analyze and compare the systemic inflammatory index (SII), which is a hematologic parameter between subjects with radiographic axial spondyloarthritis, non-radiographic axial spondyloarthritis, and healthy controls. Secondarily, the relationship between disease activity and enthesitis score and SII scores in patients with radiographic and non-radiographic axial spondyloarthritis will be investigated.

Status (registry)
Suspended
Study type
Observational
Enrollment
300 (estimated)
First submitted
4 Jul 2022
Start date
15 Jul 2022
Primary completion date
15 Feb 2026
Lead sponsor
Bozyaka Training and Research Hospital
NCT number
NCT05450133

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Acute/chronic infections
  • Presence of other autoimmune diseases
  • Diabetes mellitus
  • Coronary arterial disease
  • Hypertension
  • Malignancy
  • Hematological diseases
  • Liver diseases
  • Renal diseases

Other

  • Pregnancy/Lactation

Who the study is looking for

  • Diagnosed with axial spondyloarthritis according to the ASAS classification criteria

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Izmir Bozyaka Research and Training HostpitalIzmirTürkiyeUnknown status

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