NCT05454124Recruiting
Factors in Learning And Plasticity: Macular Degeneration
Characterization of Multiple Factors in Training and Plasticity in Central Vision Loss: Macular Degeneration
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging population are consistent with the mission of the NIA.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 5 Jul 2022
- Start date
- 1 Nov 2022
- Primary completion date
- Nov 2026
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Macular degeneration
- NCT number
- NCT05454124
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Nov 2022 to the primary completion date, Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous serious head injury
Other
- Pacemaker or any ferromagnetic metal implanted in their body
- Metal of any type implanted in their head (limited dental work is acceptable)
- Claustrophobia
- Being hearing-impaired
- Weight over 300 pounds
- Maximum body girth over 60 inches
- Presence of hallucinations or delusions
- Excessive old, or colorful tattoos, especially near the head
- Pregnancy
- Braces/permanent retainer
Who the study is looking for
- Aged 18-89
- Severely impaired vision in both eyes (20/100 or worse)
- diagnosis of Macular Degeneration by an Ophthalmologist
- Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (MAIA)
- Medical record review indicating this level of disease severity has been present for at least 2 years
- Reside within 50 miles of study site
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UAB Coordinator of this site? Confirm its status | Birmingham | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.