NCT05457127Not yet recruiting
Obstructive Sleep Apnea Treatment in Serious Mental Illness
Obstructive Sleep Apnea Treatment in People Aging With Serious Mental Illness
Source: ClinicalTrials.gov · Last updated 10 Jul 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Serious mental illnesses (SMI) like schizophrenia and bipolar disorder are two of the most disabling and costly chronic illnesses worldwide. A high proportion of adults with schizophrenia and bipolar disorder have sleep disorders, like obstructive sleep apnea (OSA), but tend to be underdiagnosed and undertreated compared to the general population. This study aims to examine feasibility, acceptance, and impact of OSA treatment and how it affects cognitive function in people with SMI.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 22 Jun 2022
- Start date
- 1 Jan 2025
- Primary completion date
- Nov 2026
- Lead sponsor
- University of California, San Diego
- Diseases
- Schizophrenia, Bipolar disorder
- NCT number
- NCT05457127
What you commit to
- Study type: Interventional
- Planned participants: 300
- From 1 Jan 2025 to the primary completion date, Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Diagnosis of OSA and currently receiving APAP, CPAP, or any treatment from a physician.
Other illness
- Diagnosis of dementia, mental retardation, or other neurological or medical conditions known to affect neurophysiologic or neurocognitive functioning, or autoimmune disease
- Other major DSM-IV-TR Axis I Disorder
Other
- DSM-IV-TR diagnosis of active alcohol or other substance abuse or dependence in the 3 months preceding enrollment. This will be self-report.
- Medical problems that interfere with a participant's ability to complete the assessments
- Plans to move out of the San Diego county area within the following 6 months
Who the study is looking for
- Control participants:
- lifetime absence of major psychiatric illness
- 40 to 70 years old
- be at risk for or have a diagnosis of obstructive sleep apnea
- For participants with serious mental illness:
- diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder
- must not be conservatized
- 40 - 70 years old
- be at risk or have a diagnosis of obstructive sleep apnea.
Age in the registry: 40 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCSD Coordinator of this site? Confirm its status | La Jolla | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.