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NCT05459909Active, not recruiting

The Effect of Synbiotic and Diet Modification Among Overweight or Obese Hong Kong Chinese

A Study of the Effect of Synbiotic Supplementation and/or Dietary Intervention With Fruits and Vegetables on the Risk of Metabolic Dysfunction and Overweight or Obesity Among Hong Kong Chinese

Source: ClinicalTrials.gov · Last updated 9 Jun 2026

Brief summary (registry, in English)

Synbiotic is a nutritional supplement that contains both prebiotic and probiotic. Probiotics are beneficial microorganisms, while prebiotics are foods that help the growth of beneficial microorganisms in the gut. In the study, dietary intervention with fruits and vegetables and/or synbiotic supplementation with be administered to Hong Kong Chinese subjects for eight weeks. Changes in the composition and diversity of intestinal microbiota, and markers indicative of obesity, chronic inflammation and metabolic dysfunction will be assessed throughout the whole period. This study will further provide a scientific basis for the intake of synbiotics for reducing the risk of overweight and obesity among Hong Kong Chinese. Furthermore, the results will bridge to further research into the most desirable gut microbiome profile, hence facilitating personalised nutrition for optimal health.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
100 (estimated)
First submitted
7 Jul 2022
Start date
Jul 2020
Primary completion date
Dec 2028
Lead sponsor
Chinese University of Hong Kong
Diseases
Obesity
NCT number
NCT05459909

What you commit to

  • Study type: Interventional
  • Planned participants: 100
  • From Jul 2020 to the primary completion date, Dec 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Using cholesterol-lowering, antihypertensive, anti-inflammatory drugs or Chinese medicines
  • Consuming laxatives, any gastrointestinal medication, probiotics, prebiotics, synbiotics or antibiotics

Other

  • Practicing dietary restrictions
  • Smokers
  • Alcohol abuser
  • Currently pregnant or lactating

Who the study is looking for

  • Waist circumference ≥90cm in men and ≥80cm in women
  • BMI \>23.0kg/m2

Age in the registry: 20 years to 95 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The Chinese University of Hong Kong
Coordinator of this site? Confirm its status
ShatinHong Kong SAR ChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.