NCT05467306Active, not recruiting
Enhancing PrEP Outcomes Among Kenyan Adolescent Girls and Young Women With a Novel Pharmacy-based PrEP Delivery Platform
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
The investigators will conduct a cluster RCT in Kisumu, Kenya to determine the effect of nurse-navigators on PrEP initiation, persistence, and adherence among AGYW seeking contraception within a pharmacy-based PrEP delivery model. The study will randomize 20 retail pharmacies offering PrEP (10 pharmacies per randomization arm) and will enroll 1900 AGYW seeking contraception. All participants will be enrolled following purchase of a contraceptive method, offered PrEP (daily oral PrEP or the DPV-VR) and followed for 10 months. The study will quantify and compare PrEP initiation, persistence, and adherence at the pharmacy-level between randomization arms, in addition to several secondary and exploratory outcomes.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 1900 (estimated)
- First submitted
- 13 Jul 2022
- Start date
- 17 May 2023
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- University of Washington
- Diseases
- HIV
- NCT number
- NCT05467306
What you commit to
- Study type: Interventional
- Planned participants: 1900
- From 17 May 2023 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Not seeking contraception (EC, OCP, injectables, implants, and condoms) from the retail pharmacy site
- Currently taking PrEP
Other illness
- Not willing to receive PrEP screening per national guidelines including HIV testing
Age
- Age \<14 and \>24 years old
Other
- Male gender
- Not able and/or willing to provide informed consent for participation
Who the study is looking for
- Female gender
- Seeking contraception (EC, OCP, injectables, implants, and condoms) from the retail pharmacy site
- Age between ≥14 and \<25 years old
- Willingness to receive PrEP screening per national guidelines including HIV testing
- Not currently taking PrEP
- Able and willing to provide informed consent for participation
Age in the registry: 15 years to 24 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kenya Medical Research Institute Coordinator of this site? Confirm its status | Kisumu | Kenya | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.