NCT05470998CompletedPhase 3
L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity
Clinical Study to Evaluate the Possible Efficacy and Safety of L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
This study aims to investigate the possible efficacy and safety of L-Arginine in children having Sickle Cell Disease with increased Tricuspid Regurgitant Jet Velocity
- Status (registry)
- Completed
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 17 Jul 2022
- Start date
- 25 Jul 2022
- Primary completion date
- 1 Oct 2024
- Lead sponsor
- Tanta University
- Diseases
- Sickle cell disease
- NCT number
- NCT05470998
What you commit to
- Study type: Interventional · Phase 3
- Participants enrolled: 50
- From 25 Jul 2022 to the primary completion date, 1 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with documented causes of pulmonary hypertension other than SCD.
- Allergy to L-arginine.
Lab values
- Hepatic dysfunction: serum Alanine Aminotransferase (ALT) \> 3X upper value.
- Renal dysfunction: Creatinine level greater than or equal to 1.2 mg/dl.
Other
- Another chronic hemolytic anemia.
- Patients with Asthma.
Who the study is looking for
- children having Sickle Cell Disease with increased Tricuspid Regurgitant Jet Velocity
- age 5-18 years
Age in the registry: 5 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tanta university Coordinator of this site? Confirm its status | Tanta | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.