NCT05471037Active, not recruiting
Different Limb Lengths in Gastric Bypass Surgery (SLIM) - Part 3: Metabolism and Inflammation
Swiss Multicenter Randomized Controlled Trial on Different Limb Lengths in Gastric Bypass Surgery (SLIM Trial) - Part 3: Metabolic Mechanisms and Inflammatory Response
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
Investigation of underlying metabolic mechanisms and impact on the two surgical procedures on inflammatory factors.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 65 (estimated)
- First submitted
- 21 Mar 2022
- Start date
- 1 Aug 2022
- Primary completion date
- 1 Oct 2026
- Lead sponsor
- University Hospital, Basel, Switzerland
- Diseases
- Obesity
- NCT number
- NCT05471037
What you commit to
- Study type: Interventional
- Planned participants: 65
- From 1 Aug 2022 to the primary completion date, 1 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- general contraindications to kind of surgery
- intake of corticosteroids, anti-inflammatory/ immunosuppressive drugs potentially altering immune cells
- drug abuse
Other illness
- inability to follow the procedures of the study, e.g. due to language problems, psychological disorders etc. of the participant
- inflammatory bowel disease
- diabetes
- clinical signs of current infection
- known immunodeficiency, e.g. HIV
- known adrenal insufficiency and/or substitution with glucocorticoids
- known uncontrolled congestive heart failure
- known uncontrolled malignant disease
Lab values
- known anemia (e.g. hemoglobin \< 110g/L for males, \< 100g/L for females)
- known neutropenia (e.g. leucocyte count \< 1.5 x 10\^9/L or ANC \< 0.5 x 10\^9/L)
Other
- known or suspected non-compliance
- participation in another interventional study
- BMI \> 60 kg/m2
- height \< 145 cm
- CL length of \< 180 cm as measured intraoperatively
- ASA physical status classification \> III
- known vasculitis, collagenosis
- risky daily alcohol consumption (\> 24g/d for males, \> 12g/d for females)
- known liver cirrhosis Child B or C
- currently pregnant or breastfeeding
Who the study is looking for
- 2 x 25 patients with morbid obestiy (BMI of 35 kg/m2 or higher) who comply with the regulatory rules for bariatric surgery in Switzerland (SMOB guidelines) and participate in the SLIM Trial
- 15 healthy lean controls
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St Clara Research Ltd, St Claraspital Basel Coordinator of this site? Confirm its status | Basel | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.