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NCT05472597Enrolling by invitation

Continuation of the nuMoM2b Heart Health Study

Source: ClinicalTrials.gov · Last updated 1 Jul 2026

Brief summary (registry, in English)

Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women. The nuMoM2b Heart Health Study (nuMoM2b-HHS) has followed a demographically diverse cohort of women enrolled and richly phenotyped during their first pregnancy, with data and biospecimens prospectively collected for up to 7 years thereafter. The overarching scientific goal of this study is to define the relationship between adverse pregnancy outcomes (APOs) and CVD to optimize CVD prediction, prevention, and treatment strategies for women. Continued follow-up of this observational cohort, building on a foundation of existing high-quality data, biospecimens, and administrative structures with a robust framework for ancillary study development and implementation, provides a unique opportunity to address knowledge gaps regarding the early mechanisms and trajectory of CVD in women.

Status (registry)
Enrolling by invitation
Study type
Observational
Enrollment
4048 (estimated)
First submitted
7 Jul 2022
Start date
29 Nov 2022
Primary completion date
Jan 2027
Lead sponsor
RTI International
NCT number
NCT05472597

What you commit to

  • Study type: Observational
  • Planned participants: 4048
  • From 29 Nov 2022 to the primary completion date, Jan 2027
  • 14 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Withdrawal from study.
  • Current pregnancy.
  • Withdrawal from study.

Who the study is looking for

  • Completed one or more interval contacts during the nuMoM2b Heart Health Study.
  • Able to speak or read in English or Spanish.
  • Completed one or more interval contacts during the nuMoM2b Heart Health Study.
  • At least 18 years of age.
  • Self-report of at least 3 months postpartum from any subsequent pregnancy.
  • Provision of signed informed consent for the HHS2 study visit.
  • Able to speak or read English or Spanish.

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (14)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Northwestern University
Coordinator of this site? Confirm its status
ChicagoUnited StatesUnknown status
Case Western Reserve University/The MetroHealth System
Coordinator of this site? Confirm its status
ClevelandUnited StatesUnknown status
Indiana University
Coordinator of this site? Confirm its status
IndianapolisUnited StatesUnknown status
Intermountain Medical Center
Coordinator of this site? Confirm its status
MurrayUnited StatesUnknown status
Christiana Care Health Services
Coordinator of this site? Confirm its status
NewarkUnited StatesUnknown status
Columbia University Medical Center
Coordinator of this site? Confirm its status
New YorkUnited StatesUnknown status
McKay-Dee Hospital
Coordinator of this site? Confirm its status
OgdenUnited StatesUnknown status
University of California Irvine Medical Center
Coordinator of this site? Confirm its status
OrangeUnited StatesUnknown status
Pennsylvania Hospital
Coordinator of this site? Confirm its status
PhiladelphiaUnited StatesUnknown status
Hospital of the University of Pennsylvania
Coordinator of this site? Confirm its status
PhiladelphiaUnited StatesUnknown status
Magee Womens Research Institute
Coordinator of this site? Confirm its status
PittsburghUnited StatesUnknown status
Utah Valley Hospital
Coordinator of this site? Confirm its status
ProvoUnited StatesUnknown status
University of Utah
Coordinator of this site? Confirm its status
Salt Lake CityUnited StatesUnknown status
LDS Hospital
Coordinator of this site? Confirm its status
Salt Lake CityUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.