NCT05472597Enrolling by invitation
Continuation of the nuMoM2b Heart Health Study
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women. The nuMoM2b Heart Health Study (nuMoM2b-HHS) has followed a demographically diverse cohort of women enrolled and richly phenotyped during their first pregnancy, with data and biospecimens prospectively collected for up to 7 years thereafter. The overarching scientific goal of this study is to define the relationship between adverse pregnancy outcomes (APOs) and CVD to optimize CVD prediction, prevention, and treatment strategies for women. Continued follow-up of this observational cohort, building on a foundation of existing high-quality data, biospecimens, and administrative structures with a robust framework for ancillary study development and implementation, provides a unique opportunity to address knowledge gaps regarding the early mechanisms and trajectory of CVD in women.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 4048 (estimated)
- First submitted
- 7 Jul 2022
- Start date
- 29 Nov 2022
- Primary completion date
- Jan 2027
- Lead sponsor
- RTI International
- Diseases
- High blood pressure
- NCT number
- NCT05472597
What you commit to
- Study type: Observational
- Planned participants: 4048
- From 29 Nov 2022 to the primary completion date, Jan 2027
- 14 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Withdrawal from study.
- Current pregnancy.
- Withdrawal from study.
Who the study is looking for
- Completed one or more interval contacts during the nuMoM2b Heart Health Study.
- Able to speak or read in English or Spanish.
- Completed one or more interval contacts during the nuMoM2b Heart Health Study.
- At least 18 years of age.
- Self-report of at least 3 months postpartum from any subsequent pregnancy.
- Provision of signed informed consent for the HHS2 study visit.
- Able to speak or read English or Spanish.
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (14)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Case Western Reserve University/The MetroHealth System Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| Indiana University Coordinator of this site? Confirm its status | Indianapolis | United States | Unknown status |
| Intermountain Medical Center Coordinator of this site? Confirm its status | Murray | United States | Unknown status |
| Christiana Care Health Services Coordinator of this site? Confirm its status | Newark | United States | Unknown status |
| Columbia University Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| McKay-Dee Hospital Coordinator of this site? Confirm its status | Ogden | United States | Unknown status |
| University of California Irvine Medical Center Coordinator of this site? Confirm its status | Orange | United States | Unknown status |
| Pennsylvania Hospital Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Hospital of the University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| Magee Womens Research Institute Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| Utah Valley Hospital Coordinator of this site? Confirm its status | Provo | United States | Unknown status |
| University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
| LDS Hospital Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.