NCT05473637Recruiting
Taiwan Associated Genetic and Nongenetic Small Vessel Disease
Deciphering, Construction and Validation of Magnetic Resonance Imaging Maps, Clinical Features and Outcomes in Genetic and Nongenetic Cerebral Small Vessel Diseases
Source: ClinicalTrials.gov · Last updated 20 Jan 2026
Brief summary (registry, in English)
The TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD genes, and patients will be divided into genetic or non-genetic groups accordingly. Their clinical features and outcome will be followed for at least 2 years.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 18 Jul 2022
- Start date
- 1 Jan 2019
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Stroke, Fabry disease
- NCT number
- NCT05473637
What you commit to
- Study type: Observational
- Planned participants: 500
- From 1 Jan 2019 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- MRI evidence of CSVD due to other inflammatory, malignancy, or structural lesions
Other
- patients or family members not willing to sign informed consent
Who the study is looking for
- Participants must have at least one of the following symptoms/signs or history
- stroke (especially small vessel occlusion type of ischaemic stroke, spontaneous ICH or young stroke)
- cognitive impairment or dementia
- gait disturbance
- parkinsonism (especially vascular parkinsonism features)
- headache (especially migraine)
- positive family history of hereditary CSVD
- MRI evidence of CSVD (MRI may be done for other reasons), including mild to moderate white matter hyper intensity, any lacune, or any cerebral microbleed
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Neurology, National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.