NCT05475236Completed
Neural Underpinnings of Turning
Brain Networks of Turning Performance With Aging and Stroke
Source: ClinicalTrials.gov · Last updated 11 Jun 2025
Brief summary (registry, in English)
Older adults and stroke survivors often have difficulty performing complex walking tasks, due in part to changes in the brain. One task often overlooked is turning, which can lead to injury when performed poorly. The investigators will use non-invasive brain stimulation to assess brain activity and relate those observations to turning performance in older adults and stroke survivors.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 16 (actual)
- First submitted
- 15 Jul 2022
- Start date
- Feb 2023
- Primary completion date
- Jun 2024
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Stroke
- NCT number
- NCT05475236
What you commit to
- Study type: Interventional
- Participants enrolled: 16
- From Feb 2023 to the primary completion date, Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of medications affecting the central nervous system
- myocardial infarction or major heart surgery in the previous year
- bone fracture or joint replacement in the previous six months
- current participation in physical therapy for lower extremity function or cardiopulmonary rehabilitation
Other illness
- Diagnosed neurological disorder or injury of the central nervous system, or observation of symptoms consistent with such a condition (Alzheimer's, Parkinson's, stroke, etc.)
- current cardiovascular, lung or renal disease; diabetes; terminal illness
- cancer treatment in the past year, except for nonmelanoma skin cancers and cancers having an excellent prognosis (e.g., early stage breast or prostate cancer)
- current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder
- uncontrolled hypertension at rest (systolic \> 180 mmHg and/or diastolic \> 100 mmHg)
Other
- Contraindications to non-invasive brain stimulation (e.g., metal in head, wound on scalp)
- Contraindications to magnetic resonance imaging (e.g., metal in body, claustrophobia, etc).
- severe arthritis, such as awaiting joint replacement
- severe obesity (body mass index \> 35)
- current enrollment in any clinical trial
- difficulty communicating with study personnel, and/or non-English speaking
- planning to relocate out of the area during the study period
- clinical judgment of investigative team regarding safety or non-compliance
Who the study is looking for
- age 65 years or older
- preferred 10m walking speed \< 1.1 m/s
- self-report of "some difficulty with walking tasks, such as becoming tired when walking a quarter mile, or when climbing two flights of stairs, or when performing household chores."
- Willingness to be randomized to either study group and to participate in all aspects of study assessment and intervention
Age in the registry: 65 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| North Florida/South Georgia Veterans Health System, Gainesville, FL Coordinator of this site? Confirm its status | Gainesville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.