NCT05476627Recruiting
Risk Factors and Multiomics Study of Chronic Kidney Disease Caused by Metabolic Diseases
Source: ClinicalTrials.gov · Last updated 16 Aug 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
With the development of China's economy, people's living standard have improved, and the dietary structure have changed. Metabolic diseases, such as hypertension, diabetes, hyperuricemia and obesity have gradually become an important health burden in China. The pathophysiological mechanism of renal injury caused by metabolic diseases has always been a hotspot of research. Currently, it is believed that various mechanisms including the activation of Renin-Angiotensin-Aldosterone System, vascular endothelial dysfunction, oxidative stress and inflammatory process may be involved. Although there are differences in renal pathological manifestations caused by different metabolic diseases, the kidney will eventually present ischemic changes and fibrosis with the progression of the disease. So there must be some common pathogenesis. This study is designed to build a disease cohort of patients with chronic kidney disease caused by metabolic diseases, to identify risk factors leading to disease progression and to explore biomarkers for early diagnosis and treatment of kidney damage.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 25 Jul 2022
- Start date
- 1 Jul 2022
- Primary completion date
- 1 Jul 2025
- Lead sponsor
- Peking Union Medical College Hospital
- Diseases
- Chronic kidney disease, Obesity, High blood pressure
- NCT number
- NCT05476627
What you commit to
- Study type: Observational
- Planned participants: 200
- From 1 Jul 2022 to the primary completion date, 1 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with primary and secondary glomerular diseases
- Patients with other comorbidities that could affect the volume or the components of the kidney, such as renal cysts, polycystic kidney disease, medullary sponge kidney, hydronephrosis, renal artery stenosis, renal vein thrombosis and/or renal tumors;
- Patients with unstable vital signs, failure of other organs or dysphoria.
Age
- Age \<18 yrs or \>80yrs;
Other
- Contraindications for MRI examination;
- Pregnant or lactation patients;
Who the study is looking for
- The diagnosis of metabolic diseases were confirmed;
- Be able to understand the process of the research;
- Volunteer for participation and be able to sign the informed consent.
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Peking Union Medical College Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.