NCT05480995Active, not recruitingPhase 2
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone Positron Emission Tomography-Magnetic Resonance Imaging (PET / MRI)
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
Purpose: The aim of this study is to assess the sensitivity and specificity of FFNP PET/MRI for diagnosis of endometriosis. Participants: A total of 24 participants will be recruited from individuals with clinically suspected endometriosis. Procedures (methods): This is a prospective, one arm, single center study of 24 subjects with clinically suspected endometriosis to demonstrate FFNP PET-MRI's clinical utility for diagnosis of endometriosis.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 9 (actual)
- First submitted
- 27 Jul 2022
- Start date
- 17 Jan 2023
- Primary completion date
- Aug 2026
- Lead sponsor
- University of North Carolina, Chapel Hill
- Diseases
- Endometriosis
- NCT number
- NCT05480995
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 9
- From 17 Jan 2023 to the primary completion date, Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic progestin-containing medications or Gonadotropin-releasing hormone (GnRH) analogues in the last 10-16 days (or 2 cycles in the case of GnRH analogues as these are dosed monthly) or inability to discontinue these medications
Other illness
- Known history of breast, ovarian or endometrial cancer.
Lab values
- Allergy to gadolinium contrast or Glomerular Filtration Rate (GFR) below 30 ml/min.
Other
- Male
- Institutionalized subject (prisoner or nursing home patient)
- Pregnant or breast-feeding women
Who the study is looking for
- Age 18 or older
- Female of childbearing age (18-55 years)
- Clinically suspected (symptomatic) endometriosis as defined by referring physician (this would also include endometriomas as other disease may be present).
- Scheduled for planned operative laparoscopy with no hormone treatment for at least two cycles
- Able to provide informed consent
Age in the registry: 18 years to 55 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of North Carolina at Chapel Hill Coordinator of this site? Confirm its status | Chapel Hill | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.