NCT05485558CompletedPhase 2
the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy
Clinical Study Evaluating the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy
Source: ClinicalTrials.gov · Last updated 1 Jul 2025
Brief summary (registry, in English)
This study aims at investigating the possible efficacy and safety of N-acetyl cysteine as adjuvant therapy in the treatment of drug-resistant epilepsy
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 90 (actual)
- First submitted
- 30 Jul 2022
- Start date
- 15 Sept 2022
- Primary completion date
- 1 Jun 2024
- Lead sponsor
- Tanta University
- Diseases
- Epilepsy
- NCT number
- NCT05485558
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 90
- From 15 Sept 2022 to the primary completion date, 1 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Any metabolic conditions that might increase the risks associated with trial participation or investigational product administration, such as hepatic enzyme elevation greater than twice normal and/or a GFR \< 60 mL/min/1.73 m2 or electrolyte imbalance.
- Patients with Known allergy to N-acetyl cysteine.
- Patients taking antioxidant and/or anti-inflammatory medications
Who the study is looking for
- Patients aged 3-18 years with intractable childhood-onset epilepsy.
- All patients are diagnosed to have drug-resistant epilepsy (refractory epilepsy) according to the ILAE definition.
- The subject is willing and able to comply with the study requirements
Age in the registry: 3 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tanta university Coordinator of this site? Confirm its status | Tanta | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.